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      What medical conditions lead to a request for euthanasia? A rapid scoping review

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          Abstract

          Background and Aims

          Euthanasia is a controversial issue related to the right to die. Although euthanasia is mostly requested by terminally sick individuals, even in societies where it is legal, it is unclear what medical conditions lead to euthanasia requests. In this scoping review, we aimed to compile medical conditions for which euthanasia has been requested or performed around the world.

          Methods

          The review was preferred reporting items for systematic reviews and meta‐analysis for scoping reviews (PRISMA‐ScR) checklist. Retrieved search results were screened and unrelated documents were excluded. Data on reasons for conducting or requesting euthanasia along with the study type, setting, and publication year were extracted from documents. Human development index and euthanasia legality were also extracted. Major medical fields were used to categorize reported reasons. Group discussions were conducted if needed for this categorization. An electronic search was undertaken in MEDLINE through PubMed for published documents covering the years January 2000 to September 2022.

          Results

          Out of 3323 records, a total of 197 papers were included. The most common medical conditions in euthanasia requests are cancer in a terminal phase (45.4%), Alzheimer's disease and dementia (19.8%), constant unbearable physical or mental suffering (19.8%), treatment‐resistant mood disorders (12.2%), and advanced cardiovascular disorders (12.2%).

          Conclusion

          Reasons for euthanasia are mostly linked to chronic or terminal physical conditions. Psychiatric disorders also lead to a substantial proportion of euthanasia requests. This review can help to identify the features shared by conditions that lead to performing or requesting euthanasia

          Abstract

          What is already known about the topic?

          • Euthanasia is a challenging issue that has sparked numerous controversies around the world over the past decades.

          • There is no consensus about the criteria or guidelines that have been set for identifying a patient eligible for euthanasia in different countries.

          What this paper adds?

          • To our knowledge, this is the first scoping review to systematically list and categorize published records of euthanasia requests around the world into five broad groups.

          • We provide a picture of all euthanasia requests' frequencies in each broad group.

          • This study facilitates informing scientists and researchers about the trends of euthanasia requests during different years and in different countries around the world.

          How this study might affect research, practice, or policy?

          • This review can provide information to help clinicians and health policymakers to reach a more precise decision about the acceptance or the rejection of requests made by patients.

          • This review informs readers about all medical conditions that increase the likelihood of requesting euthanasia. Researchers should consider these conditions and conduct further research on each condition in detail.

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          Most cited references235

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          PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation

          Scoping reviews, a type of knowledge synthesis, follow a systematic approach to map evidence on a topic and identify main concepts, theories, sources, and knowledge gaps. Although more scoping reviews are being done, their methodological and reporting quality need improvement. This document presents the PRISMA-ScR (Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews) checklist and explanation. The checklist was developed by a 24-member expert panel and 2 research leads following published guidance from the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) Network. The final checklist contains 20 essential reporting items and 2 optional items. The authors provide a rationale and an example of good reporting for each item. The intent of the PRISMA-ScR is to help readers (including researchers, publishers, commissioners, policymakers, health care providers, guideline developers, and patients or consumers) develop a greater understanding of relevant terminology, core concepts, and key items to report for scoping reviews.
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            Estimating the true global burden of mental illness.

            We argue that the global burden of mental illness is underestimated and examine the reasons for under-estimation to identify five main causes: overlap between psychiatric and neurological disorders; the grouping of suicide and self-harm as a separate category; conflation of all chronic pain syndromes with musculoskeletal disorders; exclusion of personality disorders from disease burden calculations; and inadequate consideration of the contribution of severe mental illness to mortality from associated causes. Using published data, we estimate the disease burden for mental illness to show that the global burden of mental illness accounts for 32·4% of years lived with disability (YLDs) and 13·0% of disability-adjusted life-years (DALYs), instead of the earlier estimates suggesting 21·2% of YLDs and 7·1% of DALYs. Currently used approaches underestimate the burden of mental illness by more than a third. Our estimates place mental illness a distant first in global burden of disease in terms of YLDs, and level with cardiovascular and circulatory diseases in terms of DALYs. The unacceptable apathy of governments and funders of global health must be overcome to mitigate the human, social, and economic costs of mental illness.
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              Attitudes and Practices of Euthanasia and Physician-Assisted Suicide in the United States, Canada, and Europe.

              The increasing legalization of euthanasia and physician-assisted suicide worldwide makes it important to understand related attitudes and practices.
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                Author and article information

                Contributors
                hosseinmolavi@ymail.com
                Journal
                Health Sci Rep
                Health Sci Rep
                10.1002/(ISSN)2398-8835
                HSR2
                Health Science Reports
                John Wiley and Sons Inc. (Hoboken )
                2398-8835
                20 March 2024
                March 2024
                : 7
                : 3 ( doiID: 10.1002/hsr2.v7.3 )
                : e1978
                Affiliations
                [ 1 ] Student Research Committee Shiraz University of Medical Sciences Shiraz Iran
                [ 2 ] MD‐MPH Department, School of Medicine Shiraz University of Medical Sciences Shiraz Iran
                [ 3 ] School of Dentistry Shiraz University of Medical Sciences Shiraz Iran
                [ 4 ] Department of Psychiatry, CHU Nîmes & IGF CNRS‐INSERM University of Montpellier Montpellier France
                [ 5 ] CIBERSAM Madrid Spain
                [ 6 ] Thoracic and Vascular Surgery Research Center Shiraz University of Medical Sciences Shiraz Iran
                [ 7 ] MD‐MPH Department, School of Medicine, Research Center for Traditional Medicine and History of Medicine Shiraz University of Medical Sciences Shiraz Iran
                Author notes
                [*] [* ] Correspondence Hossein M. Vardanjani, MD‐MPH Department, School of Medicine, Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

                Email: hosseinmolavi@ 123456ymail.com

                Author information
                http://orcid.org/0000-0002-8731-8403
                https://orcid.org/0000-0001-7024-8894
                Article
                HSR21978
                10.1002/hsr2.1978
                10955044
                38515545
                8c402b9a-2768-487e-b041-23f2c9128f58
                © 2024 The Authors. Health Science Reports published by Wiley Periodicals LLC.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 07 February 2024
                : 01 October 2023
                : 28 February 2024
                Page count
                Figures: 4, Tables: 2, Pages: 25, Words: 12121
                Categories
                Narrative Review
                Narrative Review
                Custom metadata
                2.0
                March 2024
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.3.9 mode:remove_FC converted:21.03.2024

                assisted suicide (as),bioethics,euthanasia,mercy killing,right to die

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