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      Three-dimensional imaging of palatal muscles in the human embryo and fetus: Development of levator veli palatini and clinical importance of the lesser palatine nerve.

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          Abstract

          After palatoplasty, incomplete velopharyngeal closure in speech articulation sometimes persists, despite restoration of deglutition function. The levator veli palatini (LVP) is believed to be significantly involved with velopharyngeal function in articulation; however, the development and innervation of LVP remain obscure. The development of LVP in human embryos and fetuses has not been systematically analyzed using the Carnegie stage (CS) to standardize documentation of development.

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          Author and article information

          Journal
          Dev. Dyn.
          Developmental dynamics : an official publication of the American Association of Anatomists
          Wiley-Blackwell
          1097-0177
          1058-8388
          Feb 2016
          : 245
          : 2
          Affiliations
          [1 ] Department of Plastic and Reconstructive Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
          [2 ] Congenital Anomaly Research Center, Kyoto University Graduate School of Medicine, Kyoto, Japan.
          [3 ] Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
          [4 ] Allied Health Sciences, Kitasato University, Kanagawa, Japan.
          [5 ] Department of Systems Science, Graduate School of Informatics, Kyoto University, Kyoto, Japan.
          Article
          10.1002/dvdy.24364
          26509917
          8fe19bc4-11dd-4062-aa0c-85ebd23b6c11
          History

          Kyoto collection,human embryo,human fetus,lesser palatine nerve,levator veli palatini muscle,palatoplasty,phase-contrast imaging

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