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      Laparoscopic cholecystectomy in a case of situs inversus totalis: a review of technical challenges and adaptations

      case-report

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          Abstract

          Situs inversus totalis is a rare congenital condition, characterized by the transposition of the thoracic and abdominal viscera, resulting in a mirror image of normal anatomy. Even though situs inversus does not predispose to gall stones, a laparoscopic cholecystectomy, in a case of situs inversus, can prove to be a technically challenging procedure, especially for the right-handed surgeon. In this case report, we present an unusual case of cholelithiasis in a patient with situs inversus totalis. A laparoscopic cholecystectomy, which is considered the gold standard procedure for symptomatic gallstones, was performed. The technical challenges that were anticipated due to anatomical anomalies were managed by various preoperative and intraoperative modifications. Through this present case report, we concluded that a laparoscopic cholecystectomy is a feasible and safe procedure in patients with situs inversus totalis and can be precisely performed by a right-handed surgeon, with necessary adaptations.

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          Most cited references12

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          Laparoscopic cholecystectomy in situs inversus totalis: The importance of being left-handed.

          Since laparoscopic cholecystectomy has become the standard procedure for the treatment of gallstone disease, several cases have been reported in patients with situs inversus. These cases require more technically demanding procedures due to the symmetrical disposition of the anatomy. Thus, handedness could influence the performance of these operations. The two of us (L.M.O.) and (J.M.B.), a right-handed and a left-handed surgeon, respectively, placed the instruments in reverse mode from that used in orthotopic patients. The right-handed surgeon felt more impairment when dissecting with his left hand and decided to cross the instruments within the abdomen. The left-handed surgeon was able to alternate the performance of the dissection maneuvers between the right and left hands. Surgical procedures are apparently designed for right-handed surgeons and can be approached by the left-handed in alternative ways. In fact, the accommodation of laparoscopic cholecystectomy to left-handedness has been described in the literature. The rare opportunity to operate in a symmetrical way allows the right-handed surgeon to understand the absence of comfort and ergonomy often experienced by left-handed colleagues.
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            Reversal of left-right asymmetry: a situs inversus mutation.

            A recessive mutation was identified in a family of transgenic mice that resulted in a reversal of left-right polarity (situs inversus) in 100 percent of the homozygous transgenic mice tested. Sequences that flanked the transgenic integration site were cloned and mapped to mouse chromosome 4, between the Tsha and Hxb loci. During early embryonic development, the direction of postimplantation turning, one of the earliest manifestations of left-right asymmetry, was reversed in homozygous transgenic embryos. This insertional mutation identifies a gene that controls embryonic turning and visceral left-right polarity.
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              Laparoscopic cholecystectomy in a 39-year-old female with situs inversus.

              Kartagener syndrome consists of situs inversus, chronic sinusitis, and bronchiectasis. A 39-year-old woman known to have Kartagener syndrome presented with complaints of left upper abdominal quadrant pain. Suspicion of cholelithiasis was confirmed with ultrasound and oral cholecystogram. The patient underwent a laparoscopic cholecystectomy. Standard techniques were modified in mirror image fashion to provide access to the left upper quadrant. This unusual presentation of chronic calculus cholecystitis in a patient with Kartagener syndrome demonstrates the adaptability of laparoscopic cholecystectomy technique.
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                Author and article information

                Journal
                Ann Hepatobiliary Pancreat Surg
                Ann Hepatobiliary Pancreat Surg
                AHBPS
                Annals of Hepato-Biliary-Pancreatic Surgery
                Korean Association of Hepato-Biliary-Pancreatic Surgery
                2508-5778
                2508-5859
                May 2017
                23 May 2017
                : 21
                : 2
                : 84-87
                Affiliations
                Department of Surgery, B.R. Singh Hospital and Centre for Medical Education and Research, Eastern Railways, Kolkata, West Bengal, India.
                Author notes
                Corresponding author: Azhar Alam. Department of Surgery, B.R. Singh Hospital and Centre for Medical Education and Research, Eastern Railways, 18 C, Smith Lane, 4th Floor, Kolkata 700013, West Bengal, India. Tel: +918017306836, azharalam01@ 123456gmail.com
                Article
                10.14701/ahbps.2017.21.2.84
                5449369
                28567452
                902fa809-15d6-40c7-822e-883d8ef98db7
                Copyright © 2017 by The Korean Association of Hepato-Biliary-Pancreatic Surgery

                This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 24 December 2016
                : 27 January 2017
                : 02 February 2017
                Categories
                Case Report

                laparoscopic cholecystectomy,situs inversus totalis,adaptations

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