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      Comparison between pernasal flocked swabs and nasopharyngeal aspirates for detection of common respiratory viruses in samples from children.

      Journal of Clinical Microbiology

      Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Nasopharynx, virology, Nose, Prospective Studies, Sensitivity and Specificity, Specimen Handling, methods, Virology, Viruses, isolation & purification

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          Abstract

          In this prospective study we compared the use of pernasal flocked swab samples with the use of nasopharyngeal aspirate (NPA) samples for the detection of respiratory viruses from 455 children less than 5 years of age. Overall, the sensitivity and the specificity of the pernasal flocked swab samples were 98.5% and 100%, respectively. The excellent sensitivity of the flocked swab samples in combination with the rapid means by which they may be collected makes them an alternative to NPA samples, whose collection is more invasive.

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          Author and article information

          Journal
          18480225
          2446924
          10.1128/JCM.00369-08

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