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      Intractable hiccup due to giant hydronephrosis: A rare case report and literature review

      case-report

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          Highlights

          • A rare disease was reported in our case: giant hydronephrosis in adult patients.

          • we reported for the first time that intractable hiccups due to hydronephrosis.

          • Intractable Hiccup of the patient disappeared after nephrectomy.

          Abstract

          Introduction

          Giant hydronephrosis (GH) is a rare disease that is found in adult patients. Although there are some common symptoms associated with hydronephrosis, such as surrounding organ compressed, its rarer symptoms can render diagnosis very difficult, and treatment should also vary according to the cause.

          Presentation of case

          We here report an 82-year-old man who was admitted to the hospital for repeated intractable hiccups. After B-ultrasound and CT examination, the patient underwent laparoscopy surgery, which was converted to open nephrectomy, and the patient’s intractable hiccup symptoms disappeared.

          Discussion

          GH is a rare disease, and its symptoms are diverse. The more unusual symptoms of cystic hypertonic compression of surrounding organs, such as intractable hiccups, should be taken into account. GH is mainly diagnosed via ultrasound examination and CT scan. The choice of treatment for GH needs to be based on the etiology and renal function of hydronephrosis, and consider malignant lesions.

          Conclusion

          Giant hydronephrosis can present rare symptoms as “intractable hiccups”. The selection of treatment should be made depending on the cause.

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          Most cited references17

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          Systemic review: the pathogenesis and pharmacological treatment of hiccups.

          Hiccups are familiar to everyone, but remain poorly understood. Acute hiccups can often be terminated by physical manoeuvres. In contrast, persistent and intractable hiccups that continue for days or months are rare, but can be distressing and difficult to treat.
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            Ureteral tumours showing a worse prognosis than renal pelvis tumours may be attributed to ureteral tumours more likely to have hydronephrosis and less likely to have haematuria.

            To demonstrate the relationships among tumour location, hydronephrosis, and tumour stage in patients with Upper Urinary Tract Urothelial Carcinoma (UUT-UC). Moreover, we want to determine whether primary tumour location is an independent predictor of prognosis in those patients.
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              Giant hydronephrosis: still a reality!

              Objective Giant hydronephrosis (GH) is a rare entity in both developed and developing countries with less than 500 cases reported in the literature. Delayed diagnosis and management of GH, can result in long-term complications like hypertension, rupture of the kidney, renal failure and malignant change. We aim to highlight the importance of this often neglected entity and build a consensus for its early diagnosis and management. Material and methods Patients with GH were thoroughly worked up, managed and followed up between June 2013 and December 2015 and epidemiologic, radiological, perioperative and follow-up data was recorded. Results A total of 35 patients (adults and children) were reported. Flank pain in adults and abdominal lump in children were the most common clinical presentation. Percutaneous nephrostomy tube was placed in all patients and detailed work up was done to reach final diagnosis. Pelvi-ureteric junction obstruction (PUJO) was the final diagnosis in 32 patients (91.4%). Kidneys were non-functioning in 13 cases (37.1%) so nephrectomies were performed. Reduction pyeloplasty with nephropexy was done in 21 patients (60%) with 81% success and 23.1% complication rates. Conclusion GH requires early diagnosis and management to prevent higher nephrectomy rate along with poor success rate of conservative surgery like pyeloplasty.
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                Author and article information

                Contributors
                Journal
                Int J Surg Case Rep
                Int J Surg Case Rep
                International Journal of Surgery Case Reports
                Elsevier
                2210-2612
                13 December 2019
                2020
                13 December 2019
                : 67
                : 134-138
                Affiliations
                [a ]Department of Urology, Beijing Aerospace General Hospital, 100076 Beijing, China
                [b ]Department of Urology, The Chinese Academy of Sciences Cancer Hospital, Beijing, China
                Author notes
                [* ]Corresponding author. xingnianzeng@ 123456hotmail.com
                Article
                S2210-2612(19)30716-3
                10.1016/j.ijscr.2019.12.013
                7021515
                32062118
                9085efe4-ce8f-4764-b932-d305cdfed07d
                © 2019 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.

                This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

                History
                : 9 October 2019
                : 5 December 2019
                : 7 December 2019
                Categories
                Article

                giant hydronephrosis,intractable hiccups,symptoms,treatment,case report

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