Gestational Hypertension and Preeclampsia in Living Kidney Donors

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Abstract

Young women wishing to become living kidney donors frequently ask whether nephrectomy will affect their future pregnancies.

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Validity of preeclampsia-related diagnoses recorded in a national hospital registry and in a postpartum interview of the women.

Sjurdur F. Olsen, A Klemmensen, Ann Tabor … (2007)

In a population-based sample, the authors examined the validity of preeclampsia and related diagnoses recorded in a mandatory Danish national hospital discharge registry and in a standardized telephone interview of women who gave birth between 1998 and 2002. Using a "gold standard" for preeclampsia defined in accordance with the guidelines from the American College of Obstetricians and Gynecologists, the authors reviewed hospital charts of 3,039 women and found that 61 of 88 preeclampsia cases (69.3%) and 24 of 55 cases of serious subtypes of preeclampsia (43.6%) were recorded as such by the registry. A total of 21 of 2,951 women without preeclampsia (0.71%) had a preeclampsia diagnosis in the registry. All registrations of serious subtypes of preeclampsia reflected true cases. The positive predictive value of a preeclampsia diagnosis in the registry was 74.4%. Including interview data reduced the sample size to 2,307 women. In this sample, of 62 women with preeclampsia, 45 (72.6%) reported in the interview to have had preeclampsia. Of 2,245 women with no preeclampsia, 31 (1.4%) reported to have had preeclampsia. The positive predictive value of the women's own report on preeclampsia was 59.2%. The authors conclude, for the purpose of etiologic studies, that the registry had acceptable validity, whereas the usefulness of self-reported information may be limited.

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Pregnancy outcomes in women with chronic kidney disease: a systematic review.

Immaculate F Nevis, Angela Reitsma, Arunmozhi Dominic … (2011)

Pregnant women with chronic kidney disease (CKD) are at risk of adverse maternal and fetal outcomes. We conducted a systematic review of observational studies that described this risk.

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Accuracy of obstetric diagnoses and procedures in hospital discharge data.

J. Keyzer, Shagufta Yasmeen, W Gilbert … (2006)

The objective of the study was to estimate the validity of obstetric procedures and diagnoses in California patient discharge data. We randomly sampled 1611 deliveries from 52 of 267 California hospitals that performed more than 678 eligible deliveries in 1992 to 1993. We compared hospital-reported procedures and diagnoses against our recoding of the same records. Cesarean, forceps, and vacuum delivery were accurately reported, with sensitivities and positive predictive values exceeding 90%. Episiotomy was underreported (70% sensitivity). Cesarean indications were reported with at least 60% sensitivity, except uterine inertia, herpes, and long labor. Among comorbidities, sensitivity exceeded 60% for chorioamnionitis, diabetes, premature labor, preeclampsia, and intrauterine death. Sensitivity was poor (less than 60%) for anemia, asthma, thyroid disorders, mental disorders, drug abuse, genitourinary infections, obesity, fibroids, excessive fetal growth, hypertension, premature rupture, polyhydramnios, and postdates. The validity of hospital-reported obstetric procedures and diagnoses varies, with moderate to high accuracy for some codes but poor accuracy for others.