The usefulness of a novel fully automated PCR-based Idylla test for detection of the BRAF V600E mutation in thyroid tissue: comparison with PNA-clamping PCR, real-time PCR and pyrosequencing.

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Abstract

The BRAF V600E mutation is the most common genetic event in papillary thyroid carcinoma (PTC). The BRAF V600E mutational status has a significant diagnostic and prognostic role in PTC since it can be detected in 32%-87% of PTC by various molecular methods.

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Journal

Journal ID (iso-abbrev): J. Clin. Pathol.

Title: Journal of clinical pathology

Publisher: BMJ

ISSN (Electronic): 1472-4146

ISSN (Print): 0021-9746

Publication date (Electronic): Mar 2017

Volume: 70

Issue: 3

Affiliations

[1 ] Department of Pathology and Medical Science, Chungnam National University School of Medicine, Daejeon, Korea.

[2 ] Biobank of Chungnam National University Hospital, Daejeon, Korea.

[3 ] Department of Pharmacology, Chungnam National University School of Medicine, Daejeon, Korea.

Article

Publisher Item ID: jclinpath-2016-204025

DOI: 10.1136/jclinpath-2016-204025

PubMed ID: 27543599

SO-VID: 924ad641-2061-452a-81db-bf6c830a28f0

History

Keywords: ENDOCRINE PATHOLOGY,MOLECULAR PATHOLOGY,THYROID

Data availability:

Keywords: ENDOCRINE PATHOLOGY, MOLECULAR PATHOLOGY, THYROID

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