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      Amide proton transfer imaging of adult diffuse gliomas: correlation with histopathological grades.

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          Abstract

          Amide proton transfer (APT) imaging is a novel molecular MRI technique to detect endogenous mobile proteins and peptides through chemical exchange saturation transfer. We prospectively assessed the usefulness of APT imaging in predicting the histological grade of adult diffuse gliomas.

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          Journal
          Journal ID (iso-abbrev): Neuro-oncology
          Title: Neuro-oncology
          ISSN (Electronic): 1523-5866
          ISSN (Print): 1522-8517
          Publication date (Electronic): Mar 2014
          Volume: 16
          Issue: 3
          Affiliations
          [1 ] Department of Molecular Imaging and Diagnosis, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan (O.T.); Department of Clinical Radiology, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan (O.T., T.Y., A.H., K.Y., K.K., H.H.); Philips Research, Hamburg, Germany (J.K.); Philips Electronics Japan, Tokyo, Japan (Y.S.); Department of Neuropathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (S.O.S., T.I.); Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan (N.H., M.M., K.Y.); Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, Texas (K.S., M.T.).
          Article
          Publisher Item ID: not158
          DOI: 10.1093/neuonc/not158
          PMC ID: 3922507
          PubMed ID: 24305718
          SO-VID: 947c089d-27b7-486f-be63-439891ec3e22
          History

          Keywords: amide proton transfer (APT) imaging,chemical exchange saturation transfer (CEST),glioma.
          Data availability:
          Keywords: amide proton transfer (APT) imaging, chemical exchange saturation transfer (CEST), glioma.

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