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      Nucleophilic difluoromethylation and difluoromethylenation of aldehydes and ketones using diethyl difluoromethylphosphonate.

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      Journal: Tetrahedron
      Publisher: Elsevier BV

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          Abstract

          New methodology for difluoromethylation and difluoromethylenation of aldehydes and ketones based on nucleophilic fluorination using diethyl difluoromethylphosphonate (1) was developed.

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          PubMed ID:: 19956351
          PMC ID:: 2632590
          DOI:: 10.1016/j.tet.2008.10.006

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