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      Luteinizing hormone-releasing hormone and its analogues: a review of biological properties and clinical uses

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      Journal of Endocrinological Investigation
      Springer Nature

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          Hypophysial responses to continuous and intermittent delivery of hypopthalamic gonadotropin-releasing hormone

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            The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes.

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              Gonadotropin-releasing hormone: one polypeptide regulates secretion of luteinizing and follicle-stimulating hormones.

              A polypeptide isolated from porcine hypothalami stimulates the release of both luteinizing hormone and follicle-stimulating hormone from the pituitaries of several species. This polypeptide has been structurally identified as (pyro)Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH(2) and synthesized. The natural and synthetic materials share biological properties. It appears that this peptide represents the hypothalamic hormone regulating the secretion of both luteinizing hormone and follicle-stimulating hormone.
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                Author and article information

                Journal
                Journal of Endocrinological Investigation
                J Endocrinol Invest
                Springer Nature
                0391-4097
                1720-8386
                July 1988
                April 9 2014
                July 1988
                : 11
                : 7
                : 535-557
                Article
                10.1007/BF03350179
                9492f748-75ec-43de-8df2-c5c3c7b13837
                © 1988
                History

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