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      Incomplete Renal Tubular Acidosis: some Clinical and Physiological Features

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          Abstract

          17 patients with recurrent calcium-containing-renal calculi were studied using the short NH<sub>4</sub>CI test and one subject with ‘incomplete renal tubular acidosis’ was identified. In retrospect the only clue to this diagnosis was a fasting, morning urine pH exceeding 6.0 units. Fasting morning urine pH, which is usually less than 6.0 in subjects who acidify normally, is proposed as a simple screening test for ‘incomplete RTA’. Modified high dose NH<sub>4</sub>CI tests and Na<sub>2</sub>SO<sub>4</sub> tests were performed in this subject and other patients with either complete or incomplete distal renal tubular acidosis. These studies suggest that the ability to lower urine pH is impaired less with the incomplete than with the complete form of the disease.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1975
          1975
          28 November 2008
          : 15
          : 2
          : 111-123
          Affiliations
          Department of Medicine, University of Vermont, Burlington, Vt.; Department of Metabolism, Walter Reed Army Institute of Research, Washington, D.C.; Department of Medicine, Medical College of Virginia, Health Sciences Division, Virginia Commonwealth University, and McGuire Veterans Administration Hospital, Richmond, Va., and the Department of Medicine, Medical University of South Carolina, Charleston, S. C.
          Article
          180502 Nephron 1975;15:111–123
          10.1159/000180502
          239357
          © 1975 S. Karger AG, Basel

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          Page count
          Pages: 13
          Categories
          Original Paper

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