Phenotypic characterization of very early-onset IBD due to mutations in the IL10, IL10 receptor alpha or beta gene: a survey of the Genius Working Group.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Early-onset inflammatory bowel disease starting within the first months of life could be due to a particular genetic defect. We set up the GENetically determined ImmUne-mediated enteropathieS (GENIUS) network and collected infants with a proven defect of the IL10 axis for accurate phenotyping of disease presentation and evolution.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Inflamm. Bowel Dis.

Title: Inflammatory bowel diseases

ISSN (Electronic): 1536-4844

ISSN (Print): 1078-0998

Publication date (Electronic): Dec 2013

Volume: 19

Issue: 13

Affiliations

[1 ] *Université Paris Descartes, Sorbonne Paris Cité, Institut Imagine, Paris, France; †Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Service de Gastroentérologie pédiatrique, Paris, France; ‡Department of Pediatric Gastroenterology, ErasmusMC-Sophia Children's Hospital, Rotterdam, the Netherlands; §Department of Gastroenterology, Great Ormond Street Hospital for Sick Children and Institute of Child Health, London, United Kingdom; ‖Pediatric Gastroenterology Unit, Centro Hospitalar do Porto, Porto, Portugal; ¶Marienhospital, Bonn, Germany; **Department of Gastroenterology, Hepatology and Feeding Disorders, The Children's Memorial Health Institute, Warsaw, Poland; ††Gastroenterologia, Endoscopia Digestiva, Epatologia e Cura del Bambino con Trapianto di Fegato, Dipartimento Salute della Donna e del Bambino, Padova, Italy; ‡‡Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Service d'anatomopathologie, Paris, France; §§Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Service de radiologie, Paris, France; ‖‖INSERM U989, Paris, France; and ¶¶INSERM U768, Paris, France.

Article

DOI: 10.1097/01.MIB.0000435439.22484.d3

PubMed ID: 24216686

SO-VID: 95f006c7-b211-4408-983c-3746924f9a5c

History

Data availability:

Comments

Comment on this article

scite_

Cited by 32

See all cited by