Calcium Concentration in the Kidney

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Abstract

(1) It has been shown that the renal papilla of the hamster, the dog and the rat contain a high concentration of calcium and that there is a concentration gradient between the papillary calcium and that of the medulla and cortex. (2) The calcium and sodium gradient between renal papilla and medulla are parallel. (3) There is a gradient between the calcium concentration in the urine and that in the papilla in the rat and dog. This is not so in the hamster but a high proportion of calcium in the hamster urine may be in the form of collodial particles. (4) In the hamster, the calcium concentrated in the papilla can be lowered by a low calcium intake but this does not lower the sodium concentration in the papilla. (5) It is suggested that the high concentration of calcium in the renal papilla is related to the formation of Randall’s plaques and may be a factor in the formation of renal stones.

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Journal ID (publisher-id): NEF

Journal ID (nlm-ta): Nephron

Journal ID (doi): 10.1159/issn.1660-8151

Title: Nephron

Publisher: S. Karger AG

ISSN (Print): 1660-8151

ISSN (Electronic): 2235-3186

Publication date Subscription-year: 1968

Publication date (Print): 1968

Publication date (Electronic): 26 November 2008

Volume: 5

Issue: 5

Pages: 352-361

Affiliations

Department of Medicine, Clinical Pathology and Clinical Pharmacology, Guy’s Hospital, London

Article

Publisher ID: 179645 Other ID: Nephron 1968;5:352–361

DOI: 10.1159/000179645

PubMed ID: 5722913

SO-VID: 96440511-40c1-4af0-9ffb-35079dcb398d

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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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Calcium Concentration in the Kidney

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Karger: Nephrology

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