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      Calcium Concentration in the Kidney

      , , ,

      Nephron

      S. Karger AG

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          Abstract

          (1) It has been shown that the renal papilla of the hamster, the dog and the rat contain a high concentration of calcium and that there is a concentration gradient between the papillary calcium and that of the medulla and cortex. (2) The calcium and sodium gradient between renal papilla and medulla are parallel. (3) There is a gradient between the calcium concentration in the urine and that in the papilla in the rat and dog. This is not so in the hamster but a high proportion of calcium in the hamster urine may be in the form of collodial particles. (4) In the hamster, the calcium concentrated in the papilla can be lowered by a low calcium intake but this does not lower the sodium concentration in the papilla. (5) It is suggested that the high concentration of calcium in the renal papilla is related to the formation of Randall’s plaques and may be a factor in the formation of renal stones.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1968
          1968
          26 November 2008
          : 5
          : 5
          : 352-361
          Affiliations
          Department of Medicine, Clinical Pathology and Clinical Pharmacology, Guy’s Hospital, London
          Article
          179645 Nephron 1968;5:352–361
          10.1159/000179645
          5722913
          © 1968 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 10
          Categories
          Paper

          Cardiovascular Medicine, Nephrology

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