Impact of LABA/LAMA combination on exercise endurance and lung hyperinflation in COPD: A pair-wise and network meta-analysis.

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Abstract

The ability to exercise is an important clinical outcome in COPD, and the improvement in exercise capacity is recognized to be an important goal in the management of COPD. Therefore, since the current interest in the use of bronchodilators in COPD is gradually shifting towards the dual bronchodilation, we carried out a meta-analysis to evaluate the impact of LABA/LAMA combination on exercise capacity and lung hyperinflation in COPD.

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Journal

Journal ID (iso-abbrev): Respir Med

Title: Respiratory medicine

Publisher: Elsevier BV

ISSN (Electronic): 1532-3064

ISSN (Print): 0954-6111

Publication date (Electronic): Aug 2017

Volume: 129

Affiliations

[1 ] Chair of Respiratory Medicine and Unit of Respiratory Clinical Pharmacology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

[2 ] Division of Respiratory Medicine, University Hospital Tor Vergata, Rome, Italy.

[3 ] Chair of Respiratory Medicine and Unit of Respiratory Clinical Pharmacology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; Division of Respiratory Medicine, University Hospital Tor Vergata, Rome, Italy.

[4 ] Division of Respiratory Medicine, Department of Medicine, Queen's University, Kingston, ON, Canada.

[5 ] Chair of Respiratory Medicine and Unit of Respiratory Clinical Pharmacology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy. Electronic address: mario.cazzola@uniroma2.it.

Article

Publisher Item ID: S0954-6111(17)30187-7

DOI: 10.1016/j.rmed.2017.06.020

PubMed ID: 28732830

SO-VID: 964e1213-2574-4197-90ab-e900e71945d2

History

Keywords: COPD,Combination,Exercise,LABA,LAMA,Meta-analysis

Data availability:

Keywords: COPD, Combination, Exercise, LABA, LAMA, Meta-analysis

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