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      Trajectories of Autism Symptom Severity Change During Early Childhood

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          Abstract

          Autism symptom severity change was evaluated during early childhood in 125 children diagnosed with autism spectrum disorder (ASD). Children were assessed at approximately 3 and 6 years of age for autism symptom severity, IQ and adaptive functioning. Each child was assigned a change score, representing the difference between ADOS Calibrated Severity Scores (CSS) at the two ages. A Decreased Severity Group (28.8%) decreased by 2 or more points; a Stable Severity Group (54.4%) changed by 1 point or less; and an Increased Severity Group (16.8%) increased by 2 or more points. Girls tended to decrease in severity more than boys and increase in severity less than boys. There was no clear relationship between intervention history and membership in the groups.

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          Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders

          Describes the Autism Diagnostic Interview-Revised (ADI-R), a revision of the Autism Diagnostic Interview, a semistructured, investigator-based interview for caregivers of children and adults for whom autism or pervasive developmental disorders is a possible diagnosis. The revised interview has been reorganized, shortened, modified to be appropriate for children with mental ages from about 18 months into adulthood and linked to ICD-10 and DSM-IV criteria. Psychometric data are presented for a sample of preschool children.
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            Clinical significance: A statistical approach to defining meaningful change in psychotherapy research.

            In 1984, Jacobson, Follette, and Revenstorf defined clinically significant change as the extent to which therapy moves someone outside the range of the dysfunctional population or within the range of the functional population. In the present article, ways of operationalizing this definition are described, and examples are used to show how clients can be categorized on the basis of this definition. A reliable change index (RC) is also proposed to determine whether the magnitude of change for a given client is statistically reliable. The inclusion of the RC leads to a twofold criterion for clinically significant change.
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              Nonparametric estimation of Shannon’s index of diversity when there are unseen species in sample

              Journal of Autism and Developmental Disorders, 30(3), 205-223
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                Author and article information

                Contributors
                dgamaral@ucdavis.edu
                Journal
                J Autism Dev Disord
                J Autism Dev Disord
                Journal of Autism and Developmental Disorders
                Springer US (New York )
                0162-3257
                1573-3432
                14 May 2020
                14 May 2020
                2021
                : 51
                : 1
                : 227-242
                Affiliations
                [1 ]GRID grid.27860.3b, ISNI 0000 0004 1936 9684, Department of Psychology, , University of California Davis, ; Davis, CA USA
                [2 ]GRID grid.27860.3b, ISNI 0000 0004 1936 9684, The MIND Institute and Department of Psychiatry and Behavioral Sciences, , University of California Davis, ; 2825 50th Street, Sacramento, CA 95817 USA
                Article
                4526
                10.1007/s10803-020-04526-z
                7810617
                32410098
                98bea313-0bc9-4bcd-9dd8-ac8d8715bf12
                © The Author(s) 2020

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                Funding
                Funded by: NIH
                Award ID: R01MH103371
                Award ID: R01MH104438
                Award ID: R01MH106518
                Award ID: R01MH103284
                Award ID: T32 MH073124
                Award ID: R01MH104438
                Award Recipient :
                Funded by: MIND Institute Intellectual and Developmental Disabilities Research Center
                Award ID: U54HD079125
                Award Recipient :
                Funded by: Simons Foundation
                Funded by: Autism Center of Excellence grant awarded by NICHD
                Award ID: P50 HD093079
                Award Recipient :
                Categories
                Original Paper
                Custom metadata
                © Springer Science+Business Media, LLC, part of Springer Nature 2021

                Neurology
                autism spectrum disorder,symptom severity,early childhood,sex differences
                Neurology
                autism spectrum disorder, symptom severity, early childhood, sex differences

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