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Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography.
Bettina Drake, Gavin Collie, Giovanna Zinzalla, Edwin Nkansah, Andrew F Wilderspin, Jonathan Palmer, Stephen Neidle, Pattanathu Rahman, Kathryn Parkinson, Linh T Bui, Pankaj Shah, George Thurston, Jarmila Husby
2013-04-02
Animals, Binding Sites, Binding, Competitive, Circular Dichroism, Crystallography, X-Ray, DNA, chemistry, genetics, metabolism, Electrophoretic Mobility Shift Assay, methods, Humans, Luminescent Proteins, Models, Molecular, Nucleic Acid Conformation, Phosphopeptides, Phosphorylation, Protein Binding, Protein Structure, Secondary, Protein Structure, Tertiary, STAT3 Transcription Factor, Tyrosine
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Animals,Binding Sites,Binding, Competitive,Circular Dichroism,Crystallography, X-Ray,DNA,chemistry,genetics,metabolism,Electrophoretic Mobility Shift Assay,methods,Humans,Luminescent Proteins,Models, Molecular,Nucleic Acid Conformation,Phosphopeptides,Phosphorylation,Protein Binding,Protein Structure, Secondary,Protein Structure, Tertiary,STAT3 Transcription Factor,Tyrosine
Animals, Binding Sites, Binding, Competitive, Circular Dichroism, Crystallography, X-Ray, DNA, chemistry, genetics, metabolism, Electrophoretic Mobility Shift Assay, methods, Humans, Luminescent Proteins, Models, Molecular, Nucleic Acid Conformation, Phosphopeptides, Phosphorylation, Protein Binding, Protein Structure, Secondary, Protein Structure, Tertiary, STAT3 Transcription Factor, Tyrosine