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      Pazopanib.

      Nature reviews. Drug discovery
      Antineoplastic Agents, adverse effects, pharmacology, therapeutic use, Carcinoma, Renal Cell, drug therapy, physiopathology, Clinical Trials as Topic, Drug Delivery Systems, Humans, Kidney Neoplasms, Protein Kinase Inhibitors, Pyrimidines, Receptors, Vascular Endothelial Growth Factor, antagonists & inhibitors, Sulfonamides

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          Abstract

          In October 2009, pazopanib (Votrient; GlaxoSmithKline)--a multikinase inhibitor with targets that include vascular endothelial growth factor receptors--was approved by the US FDA for the treatment of advanced renal cell carcinoma.

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