17
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Enteric tube placement in patients with esophageal varices: Risks and predictors of postinsertion gastrointestinal bleeding

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Background and Aim

          Enteric tube (ET) placement is approached with caution in patients with esophageal varices (EV) due to concern of causing variceal bleeding. Data are limited on rates and predictors of gastrointestinal bleeding (GIB) in these patients. This study aims to assess the rate and predictors of bleeding from EV after ET placement.

          Methods

          We performed a retrospective chart review on patients requiring ET access with known EV. Inclusion criteria were age >18 with endoscopically proven EV who required ET placement. Patients who were admitted with, or developed a GIB prior to placement of ET were excluded, as were patients admitted for liver transplantation. Primary outcome was incidence of GIB within 48 h of tube placement. Secondary outcome was a >2 g/dL drop in hemoglobin within 48 h of placement without evidence of bleed. Statistical analysis was performed using Fischer's exact test, Mann–Whitney U test, and univariate logistic regression model.

          Results

          A total of 75 patients were included in the analysis. The most common etiology of cirrhosis was alcohol (44%). The most common location of EV was in the lower third of the esophagus (61%). The primary outcome was observed in 11 (14.6%) patients. The secondary outcome was found in eight (10.6%) patients. On univariate analysis, GIB was associated with higher MELD‐Na ( P = 0.026) and EV located in the lower third of the esophagus ( P = 0.048).

          Conclusion

          ET placement in patients with EV is associated with low risk of bleeding. Elevated MELD‐Na and lower EV location conferred a higher risk of bleeding after ET placement.

          Abstract

          Enteric tube placement in patients with esophageal varices (EV) is associated with low risk of bleeding. Elevated MELD‐Na and lower EV location conferred a higher risk of bleeding.

          Related collections

          Most cited references10

          • Record: found
          • Abstract: found
          • Article: not found

          Gastroenteric tube feeding: techniques, problems and solutions.

          Gastroenteric tube feeding plays a major role in the management of patients with poor voluntary intake, chronic neurological or mechanical dysphagia or gut dysfunction, and patients who are critically ill. However, despite the benefits and widespread use of enteral tube feeding, some patients experience complications. This review aims to discuss and compare current knowledge regarding the clinical application of enteral tube feeding, together with associated complications and special aspects. We conducted an extensive literature search on PubMed, Embase and Medline using index terms relating to enteral access, enteral feeding/nutrition, tube feeding, percutaneous endoscopic gastrostomy/jejunostomy, endoscopic nasoenteric tube, nasogastric tube, and refeeding syndrome. The literature showed common routes of enteral access to include nasoenteral tube, gastrostomy and jejunostomy, while complications fall into four major categories: mechanical, e.g., tube blockage or removal; gastrointestinal, e.g., diarrhea; infectious e.g., aspiration pneumonia, tube site infection; and metabolic, e.g., refeeding syndrome, hyperglycemia. Although the type and frequency of complications arising from tube feeding vary considerably according to the chosen access route, gastrointestinal complications are without doubt the most common. Complications associated with enteral tube feeding can be reduced by careful observance of guidelines, including those related to food composition, administration rate, portion size, food temperature and patient supervision.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Enteral feeding. Nasogastric, nasojejunal, percutaneous endoscopic gastrostomy, or jejunostomy: its indications and limitations.

            The following article is intended to provide a review of the current state of enteral feeding; a rapidly changing and developing field. It covers the type of feed, the routes of access, and the problems that can occur with enteral feeding.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Epidemiology of bloodstream infection associated with parenteral nutrition.

              Catheter-related bloodstream infections (CR-BSIs) occur in 1.3% to 26.2% of patients with central venous catheters used to administer parenteral nutrition (PN). Because of their nutritional components, PN solutions can support microbial growth. Contamination during preparation and handling is rare in hospitals and home-infusion pharmacies but may be difficult to control in a home setting. The risk of infection is increased in hospitalized patients because of malnutrition-associated immunosuppression, hyperglycemia exacerbated by dextrose infusion, microbial colonization/contamination of catheter hubs and the skin surrounding insertion site, and poor nursing care. During long-term catheter use for PN, an intraluminal biofilm, catheter-tip fibrin sheath or tail, or central venous thrombosis creates sites for microbial seeding and infection. Chronic conditions and psychosocial issues also increase the risk of infection. In hospitalized patients with BSIs, the most common organisms are coagulase-negative staphylococcus, Staphylococcus aureus, Enterococcus, Candida spp, Klebsiella pneumoniae, and Pseudomonas aeruginosa. In the long-term PN population, approximately 60% of CR-BSIs are caused by coagulase-negative Staphylococcus. The best plan of care for a suspected or known infected catheter in a hospitalized patient is to reinsert a new central line after 48 hours of antibiotic treatment and negative blood cultures. In patients who receive long-term PN, hospitalization increases the risk of a nosocomial infection because the catheter can be contaminated by staff. A patient with fungemia must always be admitted and catheter removed. With gram-positive and gram-negative organisms, the catheter may not need to be removed. In most patients receiving PN at home, removing a long-term venous-access device is challenging. Peripheral vein access or peripherally inserted central catheters are needed until a new permanent device can be inserted after negative blood cultures are obtained. Evaluation of remote site infection also is necessary. Strategies to reduce or prevent infection include catheter lock therapy, daily evaluation of continued need for PN, enteral rather than PN support, and avoiding overfeeding. More studies are needed to demonstrate conclusively the benefits of immunonutrition, such as the use of omega-3 or glutamine supplements to reduce CR-BSIs in patients receiving PN.
                Bookmark

                Author and article information

                Contributors
                lolwa.n.al-obaid@lahey.org
                Journal
                JGH Open
                JGH Open
                10.1002/(ISSN)2397-9070
                JGH3
                JGH Open: An Open Access Journal of Gastroenterology and Hepatology
                Wiley Publishing Asia Pty Ltd (Melbourne )
                2397-9070
                10 September 2019
                April 2020
                : 4
                : 2 ( doiID: 10.1002/jgh3.v4.2 )
                : 256-259
                Affiliations
                [ 1 ] Department of Internal Medicine Lahey Hospital and Medical Center Burlington Massachusetts USA
                [ 2 ] Department of Medicine New York‐Presbyterian/Columbia University Medical Center New York City New York USA
                [ 3 ] Division of Pulmonary and Critical Care Medicine Lahey Hospital and Medical Center Burlington Massachusetts USA
                [ 4 ] Division of Gastroenterology and Hepatology New York‐Presbyterian/Columbia University Medical Center New York City New York USA
                [ 5 ] Division of Pulmonary and Critical Care Medicine New York‐Presbyterian/Columbia University Medical Center New York City New York USA
                [ 6 ] Division of Transplantation and Hepatobiliary Diseases Lahey Hospital and Medical Center Burlington Massachusetts USA
                Author notes
                [*] [* ] Correspondence

                Lolwa N Al‐Obaid, Lahey Hospital and Medical Center, 41 Burlington Mall Road, Burlington, MA 02145, USA.

                Email: lolwa.n.al-obaid@ 123456lahey.org

                Author information
                https://orcid.org/0000-0001-8733-553X
                Article
                JGH312255
                10.1002/jgh3.12255
                7144797
                32280774
                9f935cc0-c4bb-49c8-9ade-412eaf50fefd
                © 2019 The Authors. JGH Open: An open access journal of gastroenterology and hepatology published by Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 28 July 2019
                : 16 August 2019
                Page count
                Figures: 0, Tables: 2, Pages: 4, Words: 3177
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                April 2020
                Converter:WILEY_ML3GV2_TO_JATSPMC version:5.7.9 mode:remove_FC converted:09.04.2020

                cirrhosis,enteric tubes,esophageal varices,gastrointestinal bleeding

                Comments

                Comment on this article