BRCA testing and outcomes in women with breast cancer.

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Abstract

Germline BRCA mutations (BRCAm) strongly influence the risk of developing breast cancer. This study aimed to understand the role of BRCAm testing in affected individuals and to assess its impact on the outcome of BRCAm carriers compared to non-carriers (BRCAwt) with breast cancer.

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Author and article information

Journal

Journal ID (iso-abbrev): Breast Cancer Res Treat

Title: Breast cancer research and treatment

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1573-7217

ISSN (Print): 0167-6806

Publication date (Electronic): Apr 2021

Volume: 186

Issue: 3

Affiliations

[1 ] Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA. stene032@d.umn.edu.

[2 ] Department of Pharmacy Practice and Pharmaceutical Sciences, College of Pharmacy, University of Minnesota, 1110 Kirby Drive, 232 Life Science, Duluth, MN, 55812, USA. stene032@d.umn.edu.

[3 ] AstraZeneca Pharmaceuticals, Gaithersburg, MD, USA.

[4 ] GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC, 27709, USA.

[5 ] Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, UT, USA.

[6 ] Daiichi-Sankyo, Basking Ridge, NJ, USA.

[7 ] Truven Health, Ann Arbor, MN, USA.

[8 ] University of Southern California, San Diego, CA, USA.

[9 ] Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA.

[10 ] Amgen Inc, Thousand Oaks, CA, 91320, USA.

[11 ] RTI Health Solutions, Barcelona, Spain.

[12 ] RTI Health Solutions, Waltham, MA, USA.

[13 ] AbbVie Inc, Pharmacovigilance and Patient Safety, North Chicago, IL, USA.

Article

Publisher Item ID: 10.1007/s10549-020-06038-x

DOI: 10.1007/s10549-020-06038-x

PubMed ID: 33389410

SO-VID: a13b383c-7ac3-47b7-a218-ffd21d46c807

History

Keywords: BRCA testing,Breast cancer,Survival,Systemic treatment

Data availability:

Keywords: BRCA testing, Breast cancer, Survival, Systemic treatment

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