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Mechanisms of lipid-body formation
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Abstract
Most organisms transport or store neutral lipids as lipid bodies - lipid droplets
that usually are bounded by specific proteins and (phospho)lipid. Neutral-lipid bodies
vary considerably in their morphology and are associated with an extremely diverse
range of proteins. However, the mechanisms by which they are generated in plants,
animals and microorganisms appear to share many common features: lipid bodies probably
arise from microdomains of the endoplasmic reticulum (or the plasma membrane in prokaryotes)
that contain lipid-biosynthesis enzymes, and their synthesis and size appear to be
controlled by specific protein components.