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Abstract
We report a 77-year-old man who developed Candida parapsilosis infection following
total knee arthroplasty. Knee joint effusion was noted 2 weeks after surgery, and
repeated cultures of aspirated fluid established the diagnosis of Candida parapsilosis
infection 4 weeks after surgery. Treatment consisted of debridement and lavage of
the involved joint together with continuous irrigation with fluconazole for 4 weeks,
followed by oral fluconazole for another 6 months. At 3 years follow-up, the patient
was doing well and radiological examination of the affected knee showed a firm attachment
of the prosthesis. We suggest that early identification of the causative organism
followed by continuous irrigation and use of appropriate antifungal medication may
prevent joint instability and spares the removal of the prosthesis.