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      Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494, and miR-495 increases neovascularization and blood flow recovery after ischemia.

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          Abstract

          Effective neovascularization is crucial for recovery after cardiovascular events.

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          Author and article information

          Journal
          Circ. Res.
          Circulation research
          1524-4571
          0009-7330
          Sep 26 2014
          : 115
          : 8
          Affiliations
          [1 ] From the Department of Surgery (S.M.J.W., A.J.N.M.B., R.C.M.d.J., M.R.d.V., E.A.B.P., M.C.B., P.H.A.Q., A.Y.N.) and Einthoven Laboratory for Experimental Vascular Medicine (S.M.J.W., A.J.N.M.B., R.C.M.d.J., M.R.d.V., E.A.B.P., P.H.A.Q., A.Y.N.), Leiden University Medical Center, Leiden, The Netherlands; Department of Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark (S.P.S.); and Idera Pharmaceuticals, Cambridge, MA (N.L.M., E.R.K.).
          [2 ] From the Department of Surgery (S.M.J.W., A.J.N.M.B., R.C.M.d.J., M.R.d.V., E.A.B.P., M.C.B., P.H.A.Q., A.Y.N.) and Einthoven Laboratory for Experimental Vascular Medicine (S.M.J.W., A.J.N.M.B., R.C.M.d.J., M.R.d.V., E.A.B.P., P.H.A.Q., A.Y.N.), Leiden University Medical Center, Leiden, The Netherlands; Department of Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark (S.P.S.); and Idera Pharmaceuticals, Cambridge, MA (N.L.M., E.R.K.). a.y.nossent@lumc.nl.
          Article
          CIRCRESAHA.114.304747
          10.1161/CIRCRESAHA.114.304747
          25085941
          a53e276f-c7ea-4d13-81f6-241c0d910a08
          © 2014 American Heart Association, Inc.
          History

          collateral blood circulation,microRNAs,peripheral arterial disease,physiologic angiogenesis

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