Predictive Value of Endobronchial Ultrasound Strain Elastography in Mediastinal Lymph Node Staging: The E-Predict Multicenter Study Results.

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Abstract

Systematic assessment of lymph node status by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is indicated in (suspected) lung cancer. Sampling is herein guided by nodal size and FDG-PET characteristics. Ultrasound strain elastography (SE) might further improve risk stratification. By imaging tissue deformation over time, SE computes relative tissue strain. In several tissues, a lower strain (deformation) has been associated with a higher likelihood of malignancy.

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Journal

Journal ID (iso-abbrev): Respiration

Title: Respiration; international review of thoracic diseases

Publisher: S. Karger AG

ISSN (Electronic): 1423-0356

ISSN (Print): 0025-7931

Publication date (Electronic): June 4 2020

Volume: 99

Issue: 6

Affiliations

[1 ] Department of Pulmonology, Radboudumc, Nijmegen, The Netherlands.

[2 ] Medical Ultrasound Imaging Center (MUSIC), Department of Radiology, Radboudumc, Nijmegen, The Netherlands.

[3 ] Interventional Pulmonology Unit, Policlinico S. Orsola, Bologna, Italy.

[4 ] Interventional Pulmonology Unit, Dipartimento di Scienza, Mediche e Chirurgiche, Fondazione Policlinico A. Gemelli, Rome, Italy.

[5 ] Department of Pulmonology, Azienda Ospedaliera Universitaria di Careggi, Firenze, Italy.

[6 ] Pulmonology Unit, Santa Croce Hospital, Fano, Italy.

[7 ] Department of Pulmonology, Ospedale Santa Maria Bianca, Modena, Italy.

[8 ] Department of Pulmonology, Rigshopitalet, Copenhagen, Denmark.

[9 ] Department of Respiratory Medicine, Amsterdam University Medical Centers, Amsterdam, The Netherlands.

[10 ] Department of Pulmonology, Radboudumc, Nijmegen, The Netherlands, erik.vanderheijden@radboudumc.nl.

Article

Publisher Item ID: 000507592

DOI: 10.1159/000507592

PubMed ID: 32492682

SO-VID: a641befa-a133-4960-84b4-1660c4f481dd

History

Keywords: Bronchoscopy,Endobronchial ultrasound,Endobronchial ultrasound-transbronchial needle aspiration,Esophageal ultrasound,Lung cancer staging,Strain elastography,Ultrasound elastography

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Keywords: Bronchoscopy, Endobronchial ultrasound, Endobronchial ultrasound-transbronchial needle aspiration, Esophageal ultrasound, Lung cancer staging, Strain elastography, Ultrasound elastography

Predictive Value of Endobronchial Ultrasound Strain Elastography in Mediastinal Lymph Node Staging: The E-Predict Multicenter Study Results.

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New directions in predictive processing

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