<p id="P8">Protein kinases represent one of the largest gene families in eukaryotes
roles in a wide range of cell signaling processes and human diseases. Current tools
for visualizing kinase data in the context of the human kinome superfamily are limited
to encoding data through the addition of nodes to a low-resolution image of the kinome
tree. We present Coral, a user-friendly interactive web application for visualizing
both quantitative and qualitative data. Unlike previous tools, Coral can encode data
in three features (node color, node size, and branch color), allows three modes of
kinome visualization (the traditional kinome tree as well as radial and dynamic force
networks) and generates high-resolution scalable vector graphic files suitable for
publication without the need for refinement in graphic editing software. Due to its
user-friendly, interactive, and highly customizable design, Coral is broadly applicable
to high-throughput studies of the human kinome. The source code and web application
are available at
<a data-untrusted="" href="http://github.com/dphansti/Coral.html" id="d5088407e241"
<a data-untrusted="" href="http://phanstiel-lab.med.unc.edu/Coral" id="d5088407e244"