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Immunosuppressive therapy with oral prednisone to prevent restenosis after PCI. A multicenter randomized trial.
Flavio Ribichini
1 ,
Fabrizio Tomai ,
Giuseppe De Luca ,
Giacomo Boccuzzi ,
Patrizia Presbitero ,
Gabriele Pesarini ,
Valeria Ferrero ,
Anna S Ghini ,
Ramadan Abukaresh ,
Cristina Aurigemma ,
Leonardo De Luca ,
Dennis Zavalloni ,
Daniela Soregaroli ,
Paolo Marino ,
Roberto Garbo ,
Luisa Zanolla ,
Corrado Vassanelli
May 2011
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Abstract
Prednisone at immunosuppressive doses after stenting has shown remarkable efficacy in reducing ischemic recurrences in nondiabetic patients with high post-procedural levels of C-reactive protein; the study aim was to compare the clinical outcome obtained in a control group of patients treated with bare metal stents versus 2 other study groups--bare metal stent plus oral prednisone or drug eluting stents--assuming similar optimal adjunctive medical treatment.