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      Caracterización de pacientes con neoplasias de glándulas salivales mayores tratadas quirúrgicamente en un hospital universitario cubano Translated title: Characterization of patients with major salivary gland neoplasms treated surgically in a Cuban university hospital

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          Abstract

          RESUMEN Introducción: Las neoplasias de las glándulas salivales representan el grupo más heterogéneo y complejo de los procesos tumorales de la cabeza y el cuello. Objetivo: Caracterizar a los pacientes con neoplasias de glándulas salivales mayores que recibieron tratamiento quirúrgico en un hospital universitario cubano. Métodos: Se realizó un estudio observacional, descriptivo y transversal en pacientes diagnosticados histológicamente con neoplasias de glándulas salivales mayores. Las variables evaluadas fueron: edad, sexo, tipo de neoplasia, sitio primario, diagnóstico histológico y técnicas quirúrgicas. Resultados: Se estudiaron 55 pacientes con neoplasias, de las cuales 45 (81,82 %) fueron benignas, con mayor frecuencia en los hombres (n = 28; 62,22 %). La edad media de presentación de las neoplasias fue 55,11 ± 16,04 años, y el grupo de edad más afectado fue el de 40-59 años (n = 26; 47,27 %). La parótida fue la glándula más afectada (n = 48), fundamentalmente por adenomas pleomorfos (n = 28; 58,33 %). La parotidectomía subtotal fue la cirugía mayormente realizada (n = 38; 79,17 %). Conclusiones: Las neoplasias parotídeas benignas presentadas en pacientes adultos del sexo masculino fueron las más frecuentes.

          Translated abstract

          ABSTRACT Introduction: Salivary gland neoplasms are the most heterogeneous and complex group of head and neck tumoral processes. Objective: Characterize patients with major salivary gland neoplasms undergoing surgical treatment in a Cuban university hospital. Methods: A cross-sectional observational descriptive study was conducted of patients histologically diagnosed with major salivary gland neoplasms. The variables evaluated were age, sex, type of neoplasm, primary site, histological diagnosis and surgical techniques. Results: A total 55 neoplasms were studied, of which 45 (81.82%) were benign, with a higher frequency in men (n = 28; 62.22%). Mean age at neoplasm presentation was 55.11 ± 16.04 years, and the most affected age group was 40-59 years (n = 26; 47.27%). The parotid was the most frequently affected gland (n = 48), mainly by pleomorphic adenomas (n = 28; 58.33%). Subtotal parotidectomy was the most common surgical procedure (n = 38; 79.17%). Conclusions: Benign parotid gland neoplasms presenting in male adult patients were the most frequent type.

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          Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population.

          There is little information in the English-language literature about the epidemiology of salivary gland neoplasms in the eastern Chinese population. A large retrospective study (6982 primary salivary tumors during 23 years) was carried out to investigate the clinicopathological features (tumor location, patient sex and age) of these tumors in this population. 3593 tumors were in males and 3389 in females. Pleomorphic adenoma (69%) was the most common tumor and 20% were located in minor glands. 92% of Warthin's tumors occurred in males. Malignant tumors were predominantly adenoid cystic carcinoma (30%) and mucoepidermoid carcinoma (30%). Incidences of lymphoepithelial carcinomas (5%) and polymorphous low-grade adenocarcinoma (1%) of malignant tumors were identified. 28% of tumors originated from minor glands. Most findings were similar to those in the literature, with some variations. The salivary tumors slightly predominated in males. Relatively higher incidences of minor gland tumors and specifically of pleomorphic adenoma in minor glands were noted. Adenoid cystic carcinoma and mucoepidermoid carcinoma constituted the most common malignancies. There was a high incidence of lymphoepithelial carcinomas but a low incidence of polymorphous low-grade adenocarcinoma. The historical significant male predominance of Warthin's tumor was confirmed.
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            A 20-Year Review of 75 Cases of Salivary Duct Carcinoma.

            Salivary duct carcinoma is a rare, aggressive malignancy of the salivary glands. Owing to its rare nature, clinical data are limited, and only a few clinical studies comprise more than 50 patients.
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              Salivary gland tumours in a northern Chinese population: a 50-year retrospective study of 7190 cases

              The aims of this study were to investigate the epidemiological and clinical characteristics of epithelial salivary gland tumours in a northern Chinese population and to evaluate the current TNM classification system. A demographic and descriptive analysis of 7190 epithelial salivary gland tumours was performed. There were 4654 benign tumours and 2536 malignant tumours. The percentage of tumours located in the parotid, submandibular, sublingual, and minor salivary glands was 62.66%, 9.92%, 2.57%, and 24.85%, respectively; 22.26%, 35.76%, 92.97%, and 61.89% of the tumours, respectively, were malignant. Over 90% in the tongue and maxillary sinus were malignant. Warthin tumour, salivary duct carcinoma, and squamous cell carcinoma were predominant in males, while basal cell adenoma, myoepithelioma, and pleomorphic adenoma were predominant in females. Further, 2.55% of the tumours were in children and adolescents: 44.81% of the tumours were malignant, as opposed to 35.02% in adults. According to the 7th TNM classification, the percentages of T3 and stage III tumours were approximately 10%. Salivary gland tumours show distribution patterns according to histological type, location, and patient age and sex. The limitations of the current TNM classification of salivary gland carcinoma should be considered and revisions made.
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                Author and article information

                Journal
                ibi
                Revista Cubana de Investigaciones Biomédicas
                Rev Cubana Invest Bioméd
                ECIMED (Ciudad de la Habana, , Cuba )
                0864-0300
                1561-3011
                September 2021
                : 40
                : 3
                : e1136
                Affiliations
                [1] Bayamo Granma orgnameUniversidad de Ciencias Médicas de Granma orgdiv1Hospital General Universitario “Carlos Manuel de Céspedes” orgdiv2Servicio de Cirugía Maxilofacial Cuba
                Article
                S0864-03002021000400012 S0864-0300(21)04000300012
                a9d62b60-497e-498f-8ebf-a42508863398

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 24 August 2020
                : 21 November 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 33, Pages: 0
                Product

                SciELO Cuba

                Categories
                ARTÍCULOS ORIGINALES

                neoplasias de la parótida,parotid gland neoplasms,parotid gland,glándulas salivales,glándula parótida,salivary glands

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