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      Ultrasonographic Assessment of Bone Maturity in Newborns

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          Background: Traditionally, the bone maturity at birth has been estimated from the radiological presence and size of the ossified distal femoral epiphysis. This study was conducted in a search for a sonographic tool for the evaluation of neonatal bone maturity. Methods: We examined sonographically 256 neonates within 24 h of birth. Gestational ages ranged from 36 to 42 weeks (mean: 39.4; median: 40). Birth weights ranged from 1,945 to 5,000 g (mean: 3,175; median: 3,180). The distal femoral epiphysis was imaged on the coronal plane sonogram of the distal femur with the knee at 90° flexion and the distal femoral epiphysis maximal height was recorded. The acetabulum was imaged using Graf’s method in the coronal plane image and the acetabular diameter recorded. Results: It was found that plotting the distal femoral epiphysis against neonatal birth weight and gestational age provided a simple method for assessing the bone maturity. According to our study, a neonate can be regarded as bone maturity percentile X when plotting distal femoral epiphysis height or acetabulum diameter against birth weight and gestational age or when averaging the four readings. Conclusions: We suggest performing sonography of the distal femoral epiphysis as a bedside tool for the assessment of skeletal maturity in newborns.

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          Assessment of skeletal maturation in infants: comparison between two methods in hypothyroid patients.

          Conventional skeletal radiography is the standard technique for assessing skeletal age. However, radiography cannot demonstrate cartilage and is therefore of lesser value in infancy when the ossification centres are composed mainly of cartilage. By comparison, US clearly demonstrates cartilage and bone.

            Author and article information

            Horm Res Paediatr
            Hormone Research in Paediatrics
            S. Karger AG
            30 May 2002
            : 57
            : 5-6
            : 180-186
            aPediatric Orthopedics Unit and bDepartment of Pediatrics, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
            58379 Horm Res 2002;57:180–186
            © 2002 S. Karger AG, Basel

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            Page count
            Figures: 5, Tables: 3, References: 16, Pages: 7
            Original Paper


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