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      Scaled Brownian motion as a mean-field model for continuous-time random walks

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      Physical Review E
      American Physical Society (APS)

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          Abstract

          We consider scaled Brownian motion (sBm), a random process described by a diffusion equation with explicitly time-dependent diffusion coefficient D(t)=αD0tα-1 (Batchelor's equation) which, for α<1, is often used for fitting experimental data for subdiffusion of unclear genesis. We show that this process is a close relative of subdiffusive continuous-time random walks and describes the motion of the rescaled mean position of a cloud of independent walkers. It shares with subdiffusive continuous-time random walks its nonstationary and nonergodic properties. The nonergodicity of sBm does not however go hand in hand with strong difference between its different realizations: its heterogeneity ("ergodicity breaking") parameter tends to zero for long trajectories.

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          Most cited references4

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          Models of anomalous diffusion in crowded environments

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            First Steps in Random Walks

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              Random time-scale invariant diffusion and transport coefficients.

              Single particle tracking of mRNA molecules and lipid granules in living cells shows that the time averaged mean squared displacement delta2[over ] of individual particles remains a random variable while indicating that the particle motion is subdiffusive. We investigate this type of ergodicity breaking within the continuous time random walk model and show that delta2[over ] differs from the corresponding ensemble average. In particular we derive the distribution for the fluctuations of the random variable delta2[over ]. Similarly we quantify the response to a constant external field, revealing a generalization of the Einstein relation. Consequences for the interpretation of single molecule tracking data are discussed.
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                Author and article information

                Journal
                PLEEE8
                Physical Review E
                Phys. Rev. E
                American Physical Society (APS)
                1539-3755
                1550-2376
                January 2014
                January 13 2014
                : 89
                : 1
                Article
                10.1103/PhysRevE.89.012115
                aba82f47-8d8f-4585-bf7f-da9038474efd
                © 2014

                http://link.aps.org/licenses/aps-default-license

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