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      Cardiac tamponade from a giant thymoma: case report

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          Abstract

          Thymoma, the most common neoplasm of the anterior mediastinum especially in adults, accounts for 20-25% of all mediastinal tumors and 50% of anterior mediastinal masses. These tumors are routinely asymptomatic for prolonged periods of time. Pericardial tamponade is a very rare initial manifestation of a thymoma. This report presents a patient who had hemorrhagic pericardial tamponade that likely resulted from the largest symptomatic mixed type (type AB) thymoma described in the literature.

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          Thymoma: a clinicopathologic study based on the new World Health Organization classification

          Kazuo Nakagawa, Hisao Asamura, Yoshihiro Matsuno … (2003)
          Article 0 comments Cited 15 times – based on 0 reviews     Review now
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            Surgical treatment of thymic tumors.

            K Kessler, Benjamin Wright (2004)
            Thymoma is a rare neoplasm usually with an indolent growth pattern; however, local invasion and/or metastases may occur. The association with several paraneoplastic syndromes, especially myasthenia gravis, makes thymoma an interesting biologic tumor model. Surgery has been the standard of care for early stage disease with high cure rates anticipated. Multimodality therapy can result in long-term disease-free survival for patients presenting with locally advanced disease.
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              Diagnosis of thymoma.

              S Suster (2006)
              The diagnosis of thymic epithelial neoplasm has been a topic of controversy for many years. Reasons for this include the lack of predictive value associated with the morphology of these tumours and the multiplicity of classification schemes and terminologies proposed over the years. Recently, a new classification schema was introduced by the World Health Organization (WHO) in an attempt to standardise nomenclature and facilitate the diagnosis of primary thymic epithelial neoplasms. This schema, although not originally intended as a new histological classification, but rather as a means for translating equivalent terms from the various existing classifications, has represented a major step forward in this direction. However, problems still exist with the WHO schema, particularly with some of the criteria for the various histological subtypes as well as with issues of interobserver reproducibility. For this reason, we favour using a much more simplified approach to the morphological classification of thymic epithelial neoplasms. A personal approach to the morphological diagnosis of thymoma is described, with a brief explanation for the rationale for simplifying the existing diagnostic categories.
              Article 0 comments Cited 7 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): J Cardiothorac Surg
                Title: Journal of Cardiothoracic Surgery
                Publisher: BioMed Central
                ISSN (Electronic): 1749-8090
                Publication date Collection: 2012
                Publication date (Electronic): 6 February 2012
                Volume: 7
                Page: 14
                Affiliations
                [1 ]Department of Cardiovascular Surgery, Medicana Hospitals Bahcelievler, Istanbul, Turkey
                [2 ]Department of Anaesthesiology and Reanimation, Medicana Hospitals Camlica, Istanbul, Turkey
                [3 ]Department of Cardiovascular Surgery, Medicana Hospitals Camlica, Istanbul, Turkey
                Article
                Publisher ID: 1749-8090-7-14
                DOI: 10.1186/1749-8090-7-14
                PMC ID: 3298781
                PubMed ID: 22309880
                SO-VID: abc29d19-8bb8-48e1-b9e1-82a5efd5fe51
                Copyright © Copyright ©2012 Fazlıoğulları et al; licensee BioMed Central Ltd.
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 25 September 2011
                Date accepted : 6 February 2012
                Categories
                Subject: Case Report

                ScienceOpen disciplines: Surgery
                Keywords: thymectomy,mediastinal tumor (includes thymus),cardiac tumors (includes primary, metastatic),thymoma
                Data availability:
                ScienceOpen disciplines: Surgery
                Keywords: thymectomy, mediastinal tumor (includes thymus), cardiac tumors (includes primary, metastatic), thymoma

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