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Abstract
<p class="first" id="d871953e59">The fifth edition of the World Health Organization
(WHO) classification of soft tissue
and bone tumours was published in May 2020. This 'Blue Book', which is also available
digitally for the first time, incorporates an array of new information on these tumours,
amassed in the 7 years since the previous edition. Major advances in molecular characterisation
have driven further refinements in classification and the development of ancillary
diagnostic tests, and have improved our understanding of disease pathogenesis. Several
new entities are also included. This review summarises the main changes introduced
in the 2020 WHO classification for each subcategory of soft tissue and bone tumours.
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