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Abstract
We present a reduced-order model for fluid–structure interaction (FSI) simulation
of vocal fold vibration during phonation. This model couples the three-dimensional
(3D) tissue mechanics and a one-dimensional (1D) flow model that is derived from the
momentum and mass conservation equations for the glottal airflow. The effects of glottal
entrance and pressure loss in the glottis are incorporated in the flow model. We consider
both idealized vocal fold geometries and subject-specific anatomical geometries segmented
from the MRI images of rabbits. For the idealized vocal fold geometries, we compare
the simulation results from the 1D/3D hybrid FSI model with those from the full 3D
FSI simulation based on an immersed-boundary method. For the subject-specific geometries,
we incorporate previously estimated tissue properties for individual samples and compare
the results with those from the high-speed imaging experiment of in vivo phonation.
In both setups, the comparison shows good agreement in the vibration frequency, amplitude,
phase delay, and deformation pattern of the vocal fold, which suggests potential application
of the present approach for future patient-specific modeling.