Scrupulosity and contamination OCD are not associated with deficits in response inhibition.

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Abstract

Prior research has indicated a number of neuropsychological deficits in patients with OCD consistent with the cortico-striato-thalamo-cortical model of the disorder. Response inhibition (RI), defined as the inability to inhibit a prepotent response, has been identified as a possible candidate endophenotype for OCD. However, the results from previous studies of RI in OCD patients have been mixed, suggesting the possibility that some OCD dimensions may be associated with deficits in RI while others may not. The present study aimed to examine RI using a Go/No-Go (GNG) task in two OCD symptom dimensions, one of which, scrupulosity, has never been subject to neuropsychological investigation.

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Journal

Journal ID (iso-abbrev): J Behav Ther Exp Psychiatry

Title: Journal of behavior therapy and experimental psychiatry

Publisher: Elsevier BV

ISSN (Electronic): 1873-7943

ISSN (Print): 0005-7916

Publication date (Electronic): Mar 2016

Volume: 50

Affiliations

[1 ] Massachusetts General Hospital & Harvard Medical School, USA. Electronic address: jrasmussen@mgh.harvard.edu.

[2 ] Nova Southeastern University, USA.

[3 ] Massachusetts General Hospital & Harvard Medical School, USA; Texas State University, USA.

[4 ] Massachusetts General Hospital & Harvard Medical School, USA.

Article

Publisher Item ID: S0005-7916(15)30005-7

DOI: 10.1016/j.jbtep.2015.06.004

PubMed ID: 26183654

SO-VID: b1b0430b-456a-4d17-8783-377db82f6604

History

Keywords: Obsessive-compulsive disorder,Response inhibition,Scrupulosity

Data availability:

Keywords: Obsessive-compulsive disorder, Response inhibition, Scrupulosity

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