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      Sensory eye balance in surgically corrected intermittent exotropes with normal stereopsis

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      1 , a , 2 , 1 , 2
      Scientific Reports
      Nature Publishing Group

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          Abstract

          Surgery to align a deviated or strabismic eye is often done for both functional as well as cosmetic reasons. Although amblyopia is often an impediment to regaining full binocularity in strabismics in general, intermittent exotropes, because their deviation is intermittent, have no amblyopia and some degree of stereopsis. Binocular function, including a balanced ocular dominance, could be expected to be normal after surgical correction if normal levels of stereopsis and visual acuity are postsurgically achieved. Here we used a binocular phase combination paradigm to quantitatively assess the ocular dominance in a group of surgically corrected intermittent exotropes who have normal stereo and visual acuity as defined clinically. Interestingly, we found significant interocular imbalance (balance point < 0.9) in most of the surgically treated patients (8 out 10) but in none of the controls. We conclude that the two eyes may still have a residual sensory imbalance in surgically corrected strabismus even if stereopsis is within normal limits. Our study opens the possibility that a further treatment aimed at re-balancing the ocular dominance might be necessary in surgically treated intermittent exotropia to provide more efficient binocular processing in the long term.

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          Most cited references30

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          Refractive error and visual impairment in urban children in southern china.

          To assess the prevalence of refractive error and visual impairment in school-age children in a metropolitan area of southern China. Random selection of geographically defined clusters was used to identify children 5 to 15 years of age in Guangzhou. Children in 22 clusters were enumerated through a door-to-door survey and examined in 71 schools and 19 community facilities from October 2002 to January 2003. The examination included visual acuity measurements, ocular motility evaluation, retinoscopy, and autorefraction under cycloplegia and examination of the external eye, anterior segment, media, and fundus. A total of 5053 children living in 4814 households were enumerated, and 4364 (86.4%) were examined. The prevalence of uncorrected, presenting, and best-corrected visual acuity 20/40 or worse in the better eye was 22.3%, 10.3%, and 0.62%, respectively. Refractive error was the cause in 94.9% of the 2335 eyes with reduced vision, amblyopia in 1.9%, other causes in 0.4%, and unexplained causes in the remaining 2.8%. External and anterior segment abnormalities were seen in 1496 (34.3%) children, mainly minor conjunctival abnormalities. Media and fundus abnormalities were observed in 32 (0.73%) children. Myopia (spherical equivalent of at least -0.50 D in either eye) measured with retinoscopy affected 73.1% of children 15 years of age, 78.4% with autorefraction. The prevalence of myopia was 3.3% in 5-year-olds with retinoscopy and 5.7% with autorefraction. Females had a significantly higher risk of myopia. Hyperopia (+2.00 D or more) measured with retinoscopy was present in 16.7% of 5-year-olds, 17.0% with autorefraction. The prevalence of hyperopia was below 1% in 15-year-olds, with both methods. Astigmatism (cylinder of > or = 0.75 D) was present in 33.6% of children with retinoscopy and in 42.7% with autorefraction. The prevalence of reduced vision because of myopia is high in school-age children living in metropolitan Guangzhou, representing an important public health problem. One third of these children do not have the necessary corrective spectacles. Effective strategies are needed to eliminate this easily treated cause of significant visual impairment.
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            Incidence and types of childhood exotropia: a population-based study.

            To determine the incidence and types of childhood exotropia in a defined population. Retrospective, population-based cohort. All pediatric ( or=10 prism diopters) from January 1, 1985 through December 31, 1994. The medical records of all potential patients identified by the resources of the Rochester Epidemiology Project were reviewed. Incidence and types of childhood exotropia. Two hundred five cases of childhood exotropia were identified during the 10-year period, yielding an annual age- and gender-adjusted incidence of 64.1 (95% confidence interval: 55.2-72.9)/100,000 patients younger than 19 years. This rate corresponds to a prevalence of approximately 1.0% of all children younger than 11 years, with a significant decrease in the incidence during the second decade of life (P<0.001). Eighty-six percent of the children had intermittent exotropia, convergence insufficiency, or an exotropia in the setting of an abnormal central nervous system. The incidence of childhood exotropia from this population-based study is comparable to the prevalence rates in prior reports. Exotropia is most prevalent during the first decade of life, with intermittent exotropia and convergence insufficiency occurring most frequently.
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              The threshold contrast sensitivity function in strabismic amblyopia: evidence for a two type classification.

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                Author and article information

                Journal
                Sci Rep
                Sci Rep
                Scientific Reports
                Nature Publishing Group
                2045-2322
                19 August 2015
                2015
                : 5
                : 13075
                Affiliations
                [1 ]Department of Ophthalmology, First Affiliated Hospital, Anhui Medical University , Hefei, Anhui, PR China
                [2 ]McGill Vision Research, Dept. Ophthalmology, McGill University , Montreal, PQ, Canada
                Author notes
                Article
                srep13075
                10.1038/srep13075
                4541323
                26287935
                b2bb9c77-fda9-48f3-b537-7ffb2f7d84e6
                Copyright © 2015, Macmillan Publishers Limited

                This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

                History
                : 02 January 2015
                : 16 July 2015
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