Relationship between cardiovascular health metrics and physical performance in community-living people: Results from the Longevity check-up (Lookup) 7+ project

Abstract

Cardiovascular health metrics (CHMs) may predict disability independent of vascular events. Though, the link between CHMs and physical performance is unclear. This relationship was explored using data from the Longevity check-up (Lookup) 7+ project. Lookup 7+ is an ongoing cross-sectional survey conducted in unconventional settings across Italy. People who are at least 18-year-old and provide written informed consent are eligible. CHMs [i.e., smoking status, healthy diet, body mass index (BMI), blood pressure, blood cholesterol, and diabetes status] are assessed through closed questions and objective measurements. Physical performance is measured via the 5-repetition chair-stand test. Analyses included 7446 participants (55.5 ± 14.9 years; 56% women). Physical performance positively correlated with CHMs scores, such that participants who scored higher (6–7 points) completed the chair-stand test about 2 s faster than those scoring lower (1–2 points). In fully adjusted analysis, better physical performance was more frequently observed in younger, non-smoking, physically active men, with ideal BMI, and no diabetes. Our findings indicate a gradient of better physical function with increasing CHMs scores. Future investigations should establish the longitudinal effect of unhealthy behaviours and cardiovascular risk factors on physical performance and verify whether implementation of large-scale primordial cardiovascular prevention may positively impact physical fitness.

Contributors

Anna Picca: [e-mail]

Journal

Journal ID (nlm-ta): Sci Rep

Journal ID (iso-abbrev): Sci Rep

Title: Scientific Reports

Publisher: Nature Publishing Group UK (London )

ISSN (Electronic): 2045-2322

Publication date (Electronic): 5 November 2018

Publication date PMC-release: 5 November 2018

Publication date Collection: 2018

Volume: 8

Affiliations

ISNI 0000 0001 0941 3192, GRID grid.8142.f, Fondazione Policlinico Universitario “Agostino Gemelli” IRCCS, , Università Cattolica del Sacro Cuore, ; Rome, 00168 Italy

Article

Publisher ID: 34746

DOI: 10.1038/s41598-018-34746-4

PMC ID: 6218517

Copyright statement: © The Author(s) 2018

License:

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Funding

Funded by: - Università Cattolica del Sacro Cuore (D3.2 2013) - Università Cattolica del Sacro Cuore (D3.2 2015)

Funded by: Centro Studi Achille e Linda Lorenzon” (N/A)

Funded by: - Fondazione Roma (NCD Call for Proposals 2013) - Centro Studi "Achille e Linda Lorenzon" (N/A)

Funded by: - Italia Longeva (N/A) - Marche Region (N/A) - Ferrarini, Tedaldi, Fileni, Elanco (N/A) - Danone Italia (N/A) - Merck Sharp & Dohme Italia (N/A)

Categories

Subject: Article

Custom metadata

issue-copyright-statement © The Author(s) 2018