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      Soluble Receptor for Advanced Glycation End-Products Predicts Impaired Alveolar Fluid Clearance in Acute Respiratory Distress Syndrome.

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          Abstract

          Levels of the soluble form of the receptor for advanced glycation end-products (sRAGE) are elevated during acute respiratory distress syndrome (ARDS) and correlate with severity and prognosis. Alveolar fluid clearance (AFC) is necessary for the resolution of lung edema but is impaired in most patients with ARDS. No reliable marker of this process has been investigated to date.

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          Author and article information

          Journal
          Am. J. Respir. Crit. Care Med.
          American journal of respiratory and critical care medicine
          1535-4970
          1073-449X
          Jul 15 2015
          : 192
          : 2
          Affiliations
          [1 ] 1 Intensive Care Unit, Department of Anesthesiology, Critical Care and Perioperative Medicine, Estaing University Hospital.
          [2 ] 2 Clermont Université, Université d'Auvergne, Clermont-Ferrand, France.
          [3 ] 3 Department of Medical Biochemistry and Molecular Biology.
          [4 ] 4 Department of Microbiology.
          [5 ] 5 Department of Pathology, Estaing University Hospital, and.
          [6 ] 6 Department of Clinical Research and Innovation, CHU Clermont-Ferrand, Clermont-Ferrand, France; and.
          Article
          10.1164/rccm.201501-0020OC
          25932660

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