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      Ground Glass Opacities Observed in a 26-Year-Old Coronavirus Disease 2019 (COVID-19) Rule-Out Patient With a History of Vape Use

      case-report
      Author(s): 1 , , 1 , 1 , 2
      Editor(s): ,
      Publication date (Electronic, pub):
      Publication date (Electronic, collection):
      Journal: Cureus
      Publisher: Cureus
      Keywords: e-cigarette and vaping product use associated lung injury (evali), covid, ground-glass opacity, ground glass opacity

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          Abstract

          Pulmonary imaging findings in e-cigarette and vaping use associated lung injury (EVALI) and coronavirus disease 2019 (COVID-19) may be similar. One such pulmonary radiographic finding is ground glass opacities (GGOs). These GGOs present a wide differential that is narrowed down through diagnostic testing, deliberation of past medical history as well as medication use, and social history. This case presents GGOs observed in a COVID rule-out admission clinically correlated with EVALI.

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          Clinical Characteristics of Coronavirus Disease 2019 in China

          Wei-jie Guan, Zheng-yi Ni, Yu Hu … (2020)
          Abstract Background Since December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients. Methods We extracted data regarding 1099 patients with laboratory-confirmed Covid-19 from 552 hospitals in 30 provinces, autonomous regions, and municipalities in mainland China through January 29, 2020. The primary composite end point was admission to an intensive care unit (ICU), the use of mechanical ventilation, or death. Results The median age of the patients was 47 years; 41.9% of the patients were female. The primary composite end point occurred in 67 patients (6.1%), including 5.0% who were admitted to the ICU, 2.3% who underwent invasive mechanical ventilation, and 1.4% who died. Only 1.9% of the patients had a history of direct contact with wildlife. Among nonresidents of Wuhan, 72.3% had contact with residents of Wuhan, including 31.3% who had visited the city. The most common symptoms were fever (43.8% on admission and 88.7% during hospitalization) and cough (67.8%). Diarrhea was uncommon (3.8%). The median incubation period was 4 days (interquartile range, 2 to 7). On admission, ground-glass opacity was the most common radiologic finding on chest computed tomography (CT) (56.4%). No radiographic or CT abnormality was found in 157 of 877 patients (17.9%) with nonsevere disease and in 5 of 173 patients (2.9%) with severe disease. Lymphocytopenia was present in 83.2% of the patients on admission. Conclusions During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness. Patients often presented without fever, and many did not have abnormal radiologic findings. (Funded by the National Health Commission of China and others.)
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            Imaging of Vaping-Associated Lung Disease

            Travis Henry, Jeffrey P Kanne, Seth J Kligerman (2019)
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              Features, Evaluation, and Treatment of Coronavirus (COVID-19)

              (2020)
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                Author and article information

                Journal
                Journal ID (nlm-ta): Cureus
                Journal ID (iso-abbrev): Cureus
                Journal ID (issn): 2168-8184
                Title: Cureus
                Publisher: Cureus (Palo Alto (CA) )
                ISSN (Electronic): 2168-8184
                Publication date (Electronic, pub): 7 September 2020
                Publication date (Electronic, collection): September 2020
                Volume: 12
                Issue: 9
                Electronic Location Identifier: e10302
                Affiliations
                [1 ] Internal Medicine, The University of Kansas Medical Center, Kansas City, USA
                [2 ] Pulmonary and Critical Care Medicine, The University of Kansas Medical Center, Kansas City, USA
                Author notes
                Article
                DOI: 10.7759/cureus.10302
                PMC ID: 7544554
                SO-VID: b7157b39-9ef6-4601-9b88-fffbfffb74b4
                Copyright © Copyright © 2020, Patel et al.
                License:

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                Date received : 17 August 2020
                Date accepted : 7 September 2020
                Categories
                Subject: Internal Medicine
                Subject: Radiology
                Subject: Infectious Disease

                Keywords: e-cigarette and vaping product use associated lung injury (evali),covid,ground-glass opacity,ground glass opacity
                Data availability:
                Keywords: e-cigarette and vaping product use associated lung injury (evali), covid, ground-glass opacity, ground glass opacity

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