Osteogenesis of umbilical mesenchymal stem cells is enhanced in absence of DNA methyltransferase 3B (DNMT3B) through upregulating Runx2 expression.

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Abstract

Umbilical mesenchymal stem cells (UMSCs) is one of most popular regenerative medical source of bone replacement therapy in both clinical and scientific researches. However, it is still low effective to induce the osteogenesis of hUMSCs. In this study, we aimed to elucidate the roles of DNA methyltransferase 3B (DNMT3B) in the osteogenesis of hUMSCs.

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Journal

Journal ID (iso-abbrev): Eur Rev Med Pharmacol Sci

Title: European review for medical and pharmacological sciences

ISSN (Electronic): 2284-0729

ISSN (Print): 1128-3602

Publication date (Electronic): Oct 2014

Volume: 18

Issue: 20

Affiliations

[1 ] Shandong University, Jinan, China. jianminlicn@163.com.

Article

PubMed ID: 25392095

SO-VID: b768a281-e097-40bb-acd9-69100cf8ed14

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