Genome-wide DNA methylation drives human embryonic stem cell erythropoiesis by remodeling gene expression dynamics.

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Abstract

To investigate the role of DNA methylation during erythrocyte production by human embryonic stem cells (hESCs).

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Author and article information

Journal

Journal ID (iso-abbrev): Epigenomics

Title: Epigenomics

Publisher: Future Medicine Ltd

ISSN (Electronic): 1750-192X

ISSN (Print): 1750-192X

Publication date (Electronic): December 2017

Volume: 9

Issue: 12

Affiliations

[1 ] Department of Pathology, Qingdao Municipal Hospital, Affiliated with Qingdao University, 1 Jiaozhou Road, Qingdao 266000, Shandong, China.

[2 ] Vcanbio Center for Translational Biotechnology, 21 Strathmore Road, Natick, MA 01760, USA.

[3 ] Department of Critical Care Medicine, Qingdao Center Medical Group, Affiliated with Qingdao University, 127 Siliunan Road, Qingdao 266042, Shandong, China.

[4 ] Department of Pathology, College of Basic Medical Sciences, Jilin University, 126 Xinmin Avenue, Changchun 130021, China.

[5 ] Center for Translational Medicine, Central Hospital of Zibo, Affiliated with Shandong University, 54 Gongqingtuan Road, Zibo 255000, Shandong, China.