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      Naturally occurring aristolactams, aristolochic acids and dioxoaporphines and their biological activities.

      Natural Product Reports
      Aristolochiaceae, chemistry, Aristolochic Acids, isolation & purification, pharmacology, Biological Factors, classification, Lactams, Molecular Structure, Phenanthrenes, Plants, Medicinal, Porphyrins, Structure-Activity Relationship

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          Abstract

          Aristolactams, having a phenanthrene chromophore are a small group of compounds mainly found in the Aristolochiaceae together with the aristolochic acids and 4,5-dioxoaporphines. In this report, these three important classes of natural products are reviewed and classified on the basis of their oxygenation pattern. In addition the biological activities of these compounds and their general chemistry are discussed.

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