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      Manauealides, some of the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii.

      Journal of Natural Products
      Carbohydrate Sequence, Chromatography, High Pressure Liquid, Foodborne Diseases, physiopathology, Hawaii, Lyngbya Toxins, isolation & purification, pharmacology, toxicity, Macrolides, Magnetic Resonance Spectroscopy, Marine Toxins, Molecular Sequence Data, Rhodophyta, chemistry, Spectrometry, Mass, Fast Atom Bombardment, Spectrophotometry, Ultraviolet

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          Abstract

          Manauealides A-C (1-3), compounds related to debromoaplysiatoxin (5), were isolated and characterized from a red alga Gracilaria coronopifolia. Compounds 1 and 2 are presumed to be the causative toxins of G. coronopifolia food poisoning in Hawaii. Manauealide A (1) and C (3) are new macrolides, whereas manauealide B (2) is a known semisynthetic product of 5.

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