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      Response to Progressive Bicycle Exercise before and following Aortic Valve Replacement

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          Abstract

          The O<sub>2</sub> uptake response to symptom-limited progressive bicycle exercise that was performed serially before and up to 1 year after uncomplicated isolated aortic valve replacement (AVR) was evaluated in 37 patients. Before surgery, an unusually rapid exercise O<sub>2</sub> uptake response was seen in about half the patients, while the AVR appeared to result in a change in O<sub>2</sub> uptake kinetics to within normal limits in the majority of the patients within the first 3 postoperative months. The inappropriate O<sub>2</sub> uptake response was found to be associated with more significant limitation in exercise tolerance, and it appeared to be mediated not only by a pronounced exercise heart rate response but, probably, also by an exaggerated arteriovenous O<sub>2</sub> difference. These findings suggest that peripheral vascular responses in patients with chronic aortic valve disease may play a major role in the different O<sub>2</sub> uptake responses to progressive bicycle exercise. The physiological significance of O<sub>2</sub> kinetics during exercise, however, requires further study.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1983
          1983
          07 November 2008
          : 70
          : 2
          : 110-118
          Affiliations
          Division of Cardiology, Department of Medicine, University Central Hospital, University of Oulu, Finland
          Article
          173577 Cardiology 1983;70:110–118
          10.1159/000173577
          6871895
          c1e30655-2779-49b1-8941-7ad205d18536
          © 1983 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 14 September 1982
          : 09 January 1983
          Page count
          Pages: 9
          Categories
          Exercise Testing and Rehabilitation

          General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Aortic valve disease,O2 uptake kinetics,Exercise testing

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