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      Systematic review of genetic variants associated with cognitive impairment and depressive symptoms in Parkinson's disease.

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          Abstract

          Cognitive impairment and depression are among the most prevalent and most disabling non-motor symptoms in Parkinson's disease (PD). The genetic factors that are associated with these symptoms remain uncertain. This systematic review aims to summarise the prevailing evidence from all genetic association studies investigating the genetic variants associated with cognitive impairment and depressive symptoms in people with PD.

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          Author and article information

          Journal
          Acta Neuropsychiatr
          Acta neuropsychiatrica
          Cambridge University Press (CUP)
          1601-5215
          0924-2708
          Feb 2020
          : 32
          : 1
          Affiliations
          [1 ] Department of Old Age Psychiatry, Institute of Psychiatry, Psychology, & Neuroscience, King's College London, 16, De Crespigny Park, London-SE5 8AF, UK.
          [2 ] Mental Health of Older Adults and Dementia Clinical Academic Group, South London and Maudsley NHS foundation Trust, 115, Denmark Hill, London-SE5 8AQ, UK.
          Article
          S0924270819000280
          10.1017/neu.2019.28
          31292011
          c4809964-59a5-4919-bc4e-743347b81e60
          History

          Parkinson’s disease,depression,systematic review,cognition

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