40
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Pteropid bats are confirmed as the reservoir hosts of henipaviruses: a comprehensive experimental study of virus transmission.

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Bats of the genus Pteropus have been identified as the reservoir hosts for the henipaviruses Hendra virus (HeV) and Nipah virus (NiV). The aim of these studies was to assess likely mechanisms for henipaviruses transmission from bats. In a series of experiments, Pteropus bats from Malaysia and Australia were inoculated with NiV and HeV, respectively, by natural routes of infection. Despite an intensive sampling strategy, no NiV was recovered from the Malaysian bats and HeV was reisolated from only one Australian bat; no disease was seen. These experiments suggest that opportunities for henipavirus transmission may be limited; therefore, the probability of a spillover event is low. For spillover to occur, a range of conditions and events must coincide. An alternate assessment framework is required if we are to fully understand how this reservoir host maintains and transmits not only these but all viruses with which it has been associated.

          Related collections

          Author and article information

          Journal
          Am J Trop Med Hyg
          The American journal of tropical medicine and hygiene
          American Society of Tropical Medicine and Hygiene
          1476-1645
          0002-9637
          Nov 2011
          : 85
          : 5
          Affiliations
          [1 ] Commonwealth Scientific and Industrial Research Organization, Australian Animal Health Laboratory, Geelong, Australia. kim.halpin@lifetech.com
          Article
          85/5/946
          10.4269/ajtmh.2011.10-0567
          3205647
          22049055
          c58772a9-d351-41d9-a1a1-6e150bad9377
          History

          Comments

          Comment on this article