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      Redesigning ambulatory care management for uncontrolled type 2 diabetes: a prospective cohort study of the impact of a Boot Camp model on outcomes

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          Abstract

          Objective

          Type 2 diabetes care management (DCM) is challenging. Few studies report meaningful improvements in clinical care settings, warranting DCM redesign. We developed a Boot Camp to provide timely, patient-centered, technology-enabled DCM. Impact on hemoglobin A 1c (HbA 1c), emergency department (ED) visits and hospitalizations among adults with uncontrolled type 2 diabetes were examined.

          Research design and methods

          The intervention was designed using the Practical Robust Implementation and Sustainability Model to embed elements of the chronic care model. Adults with HbA 1c >9% (75 mmol/mol) enrolled between November 2014 and November 2017 received diabetes education and medication management by diabetes educators and nurse practitioners via initial clinic and subsequent weekly virtual visits, facilitated by near-real-time blood glucose transmission for 90 days. HbA 1c and risk for ED visits and hospitalizations at 90 days, and potential savings from reducing avoidable medical utilizations were examined. Boot Camp completers were compared with concurrent, propensity-matched chart controls receiving usual DCM in primary care practices.

          Results

          A cohort of 366 Boot Camp participants plus 366 controls was analyzed. Participants were 79% African-American, 63% female and 59% Medicare-insured or Medicaid-insured and mean age 56 years. Baseline mean HbA 1c for cases and controls was 11.2% (99 mmol/mol) and 11.3% (100 mmol/mol), respectively. At 90 days, HbA 1c was 8.1% (65 mmol/mol) and 9.9% (85 mmol/mol), p<0.001, respectively. Risk for 90-day all-cause hospitalizations decreased 77% for participants and increased 58% for controls, p=0.036. Mean potential for monetization of US$3086 annually per participant for averted hospitalizations were calculated.

          Conclusions

          Redesigning diabetes care management using a pragmatic technology-enabled approach supported translation of evidence-based best practices across a mixed-payer regional healthcare system. Diabetes educators successfully participated in medication initiation and titration. Improvement in glycemic control, reduction in hospitalizations and potential for monetization was demonstrated in a high-risk cohort of adults with uncontrolled type 2 diabetes.

          Trial registration number

          NCT02925312.

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          Most cited references26

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          The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients.

          To compare the abilities and associated hypoglycemia risks of insulin glargine and human NPH insulin added to oral therapy of type 2 diabetes to achieve 7% HbA(1c). In a randomized, open-label, parallel, 24-week multicenter trial, 756 overweight men and women with inadequate glycemic control (HbA(1c) >7.5%) on one or two oral agents continued prestudy oral agents and received bedtime glargine or NPH once daily, titrated using a simple algorithm seeking a target fasting plasma glucose (FPG)
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            A practical, robust implementation and sustainability model (PRISM) for integrating research findings into practice.

            Although numerous studies address the efficacy and effectiveness of health interventions, less research addresses successfully implementing and sustaining interventions. As long as efficacy and effectiveness trials are considered complete without considering implementation in nonresearch settings, the public health potential of the original investments will not be realized. A barrier to progress is the absence of a practical, robust model to help identify the factors that need to be considered and addressed and how to measure success. A conceptual framework for improving practice is needed to integrate the key features for successful program design, predictors of implementation and diffusion, and appropriate outcome measures. A comprehensive model for translating research into practice was developed using concepts from the areas of quality improvement, chronic care, the diffusion of innovations, and measures of the population-based effectiveness of translation. PRISM--the Practical, Robust Implementation and Sustainability Model--evaluates how the health care program or intervention interacts with the recipients to influence program adoption, implementation, maintenance, reach, and effectiveness. The PRISM model provides a new tool for researchers and health care decision makers that integrates existing concepts relevant to translating research into practice.
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              Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study

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                Author and article information

                Journal
                BMJ Open Diabetes Res Care
                BMJ Open Diabetes Res Care
                bmjdrc
                bmjdrc
                BMJ Open Diabetes Research & Care
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2052-4897
                2019
                13 November 2019
                : 7
                : 1
                : e000731
                Affiliations
                [1 ]MedStar Health Research Institute , Hyattsville, Maryland, USA
                [2 ]Department of Medicine, MedStar Georgetown University Hospital , Washington, District of Columbia, USA
                [3 ]departmentMedStar Diabetes Institute , MedStar Health , Columbia, Maryland, USA
                [4 ]MedStar Institute for Quality and Safety , Columbia, Maryland, USA
                [5 ]departmentBiostatistics and Biomedical Informatics , MedStar Health Research Institute , Hyattsville, Maryland, USA
                [6 ]departmentDepartment of Medicine , MedStar Union Memorial Hospital , Baltimore, Maryland, USA
                [7 ]departmentSchool of Medicine , University of Maryland , Baltimore, Maryland, USA
                [8 ]MedStar Health , Columbia, Maryland, USA
                Author notes
                [Correspondence to ] Dr Michelle F Magee; Michelle.F.Magee@ 123456Medstar.net
                Author information
                http://orcid.org/0000-0002-4692-3201
                Article
                bmjdrc-2019-000731
                10.1136/bmjdrc-2019-000731
                6861097
                c872b4fd-1aea-406e-a0c7-75925ad040df
                © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:  http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 02 July 2019
                : 23 September 2019
                : 30 September 2019
                Funding
                Funded by: BioTel;
                Award ID: Provided blood glucose monitors starter kits
                Funded by: MedStar Health;
                Award ID: Provided salary support to MedStar employees invol
                Categories
                Clinical care/Education/Nutrition
                1506
                1866
                Custom metadata
                unlocked

                delivery of care,education and behavioral interventions,treatment algorithms,outcome research

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