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      A Personalized Healthcare Monitoring System for Diabetic Patients by Utilizing BLE-Based Sensors and Real-Time Data Processing

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          Abstract

          Current technology provides an efficient way of monitoring the personal health of individuals. Bluetooth Low Energy (BLE)-based sensors can be considered as a solution for monitoring personal vital signs data. In this study, we propose a personalized healthcare monitoring system by utilizing a BLE-based sensor device, real-time data processing, and machine learning-based algorithms to help diabetic patients to better self-manage their chronic condition. BLEs were used to gather users’ vital signs data such as blood pressure, heart rate, weight, and blood glucose (BG) from sensor nodes to smartphones, while real-time data processing was utilized to manage the large amount of continuously generated sensor data. The proposed real-time data processing utilized Apache Kafka as a streaming platform and MongoDB to store the sensor data from the patient. The results show that commercial versions of the BLE-based sensors and the proposed real-time data processing are sufficiently efficient to monitor the vital signs data of diabetic patients. Furthermore, machine learning–based classification methods were tested on a diabetes dataset and showed that a Multilayer Perceptron can provide early prediction of diabetes given the user’s sensor data as input. The results also reveal that Long Short-Term Memory can accurately predict the future BG level based on the current sensor data. In addition, the proposed diabetes classification and BG prediction could be combined with personalized diet and physical activity suggestions in order to improve the health quality of patients and to avoid critical conditions in the future.

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              Glucose Biosensors: An Overview of Use in Clinical Practice

              Blood glucose monitoring has been established as a valuable tool in the management of diabetes. Since maintaining normal blood glucose levels is recommended, a series of suitable glucose biosensors have been developed. During the last 50 years, glucose biosensor technology including point-of-care devices, continuous glucose monitoring systems and noninvasive glucose monitoring systems has been significantly improved. However, there continues to be several challenges related to the achievement of accurate and reliable glucose monitoring. Further technical improvements in glucose biosensors, standardization of the analytical goals for their performance, and continuously assessing and training lay users are required. This article reviews the brief history, basic principles, analytical performance, and the present status of glucose biosensors in the clinical practice.
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                Author and article information

                Journal
                Sensors (Basel)
                Sensors (Basel)
                sensors
                Sensors (Basel, Switzerland)
                MDPI
                1424-8220
                06 July 2018
                July 2018
                : 18
                : 7
                : 2183
                Affiliations
                [1 ]U-SCM Research Center, Nano Information Technology Academy, Dongguk University, Seoul 100-715, Korea
                [2 ]Department of Industrial and Systems Engineering, Dongguk University, Seoul 100-715, Korea; udin@ 123456dongguk.edu (M.S.); fazal@ 123456dongguk.edu (M.F.I.); alexs@ 123456dongguk.edu (M.A.S.); norma@ 123456dongguk.edu (N.L.F.)
                Author notes
                [* ]Correspondence: ganjar@ 123456dongguk.edu (G.A.); jtrhee@ 123456dongguk.edu (J.R.); Tel.: +82-2-2264-8518 (J.R.)
                Author information
                https://orcid.org/0000-0002-3273-1452
                https://orcid.org/0000-0002-5640-4413
                https://orcid.org/0000-0001-9152-1108
                https://orcid.org/0000-0002-1133-3965
                Article
                sensors-18-02183
                10.3390/s18072183
                6068508
                29986473
                c8aafe8c-451e-4930-8f7c-892231c60e63
                © 2018 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 04 June 2018
                : 05 July 2018
                Categories
                Article

                Biomedical engineering
                diabetes,ble,real-time data processing,classification,forecasting
                Biomedical engineering
                diabetes, ble, real-time data processing, classification, forecasting

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