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      European Society of Cardiology quality indicators for the prevention and management of cancer therapy-related cardiovascular toxicity in cancer treatment

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          Abstract

          Aims

          To develop quality indicators (QIs) for the evaluation of the prevention and management of cancer therapy-related cardiovascular toxicity.

          Methods and results

          We followed the European Society of Cardiology (ESC) methodology for QI development which comprises (i) identifying the key domains of care for the prevention and management of cancer therapy-related cardiovascular toxicity in patients on cancer treatment, (ii) performing a systematic review of the literature to develop candidate QIs, and (iii) selecting of the final set of QIs using a modified Delphi process. Work was undertaken in parallel with the writing of the 2022 ESC Guidelines on Cardio-Oncology and in collaboration with the European Haematology Association, the European Society for Therapeutic Radiology and Oncology and the International Cardio-Oncology Society. In total, 5 main and 9 secondary QIs were selected across five domains of care: (i) Structural framework, (ii) Baseline cardiovascular risk assessment, (iii) Cancer therapy related cardiovascular toxicity, (iv) Predictors of outcomes, and (v) Monitoring of cardiovascular complications during cancer therapy.

          Conclusion

          We present the ESC Cardio-Oncology QIs with their development process and provide an overview of the scientific rationale for their selection. These indicators are aimed at quantifying and improving the adherence to guideline-recommended clinical practice and improving patient outcomes.

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          Most cited references19

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          Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

          David Moher and colleagues introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses
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            2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines:  The Task Force for cancer treatments and cardiovascular toxicity of the European Society of Cardiology (ESC).

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              2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS)

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                Author and article information

                Contributors
                Journal
                Eur Heart J Qual Care Clin Outcomes
                Eur Heart J Qual Care Clin Outcomes
                ehjqcco
                European Heart Journal. Quality of Care & Clinical Outcomes
                Oxford University Press
                2058-5225
                2058-1742
                January 2023
                31 October 2022
                31 October 2022
                : 9
                : 1
                : 1-7
                Affiliations
                Division of Applied Technology for Clinical Care, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London , James Clerk Maxwell Building, 57 Waterloo Road, London SE1 8WA, UK
                Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds , Leeds, UK
                Leeds Institute for Data Analytics, University of Leeds , Leeds, UK
                Department of Cardiology, Leeds Teaching Hospitals NHS Trust , Leeds, UK
                Division of Applied Technology for Clinical Care, Florence Nightingale Faculty of Nursing, Midwifery & Palliative Care, King's College London , James Clerk Maxwell Building, 57 Waterloo Road, London SE1 8WA, UK
                Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds , Leeds, UK
                Leeds Institute for Data Analytics, University of Leeds , Leeds, UK
                Department of Cardiology, Leeds Teaching Hospitals NHS Trust , Leeds, UK
                Baghdad Heart Center, Baghdad Teaching Hospital, Medical City , Baghdad, Iraq
                Scientific Council of Cardiology, Iraqi Board for Medical Specializations , Baghdad, Iraq
                Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Division of Research and Innovation, Akershus University Hospital , Lørenskog, Norway
                Department of Cardiology, Division of Medicine, Oslo University Hospital , Ullevål, Oslo, Norway
                School of Medicine, Insubria University , Varese, Italy
                LARC (Laboratorio Analisi e Ricerca Clinica) , C.so Venezia 10, Turin, Italy
                Department of Pulmonary Circulation, Thromboembolic Diseases and Cardiology, Centre of Postgraduate Medical Education , Otwock, Poland
                Institute of Hematology and Transfusion Medicine , Warsaw, Poland
                Research Medical Unit INSERM U-942, University of Paris , Paris, France
                Cardiology Department, Hôpitaux de Paris , Hôpital Lariboisière 2 Rue Ambroise Paré, Paris, France
                Department of Internal Medicine III, Cardiology, Angiology, Intensive Care Medicine, Saarland University Medical Center , Homburg, Germany
                MSC National Research Institute of Oncology , Garnarska 11, 31-115 Krakow, Poland
                Jefe Servicio Oncología Médica, Hospital Universitario Ramón y Cajal , Madrid, Spain
                Newcastle Centre of Excellence in Cardio-Oncology, Calvary Mater Newcastle, Hunter Medical Research Institute, John Hunter Hospital, University of Newcastle , NSW, Australia
                Cardio-Oncology Unit, Department of Translational Medical Sciences (DISMET), Center for Basic and Clinical Immunology Research (CISI), Interdepartmental Center for Clinical and Translational Research (CIRCET), Interdepartmental Hypertension Research Center (CIRIAPA), Federico II University , Naples, Italy
                Cardio-oncology Program, MedStar Heart and Vascular Institute , Washington DC, USA
                Department of Cardiology, Mauriziano Hospital , Turin, Italy
                University Hospital Ramon y Cajal , Madrid, Spain
                Department of Community Cardiology, Clalit Health Services, Tel Aviv Jaffa , Israel
                Faculty of Health Sciences, Ben Gurion University of the Negev , Beersheba, Israel
                University Hospital Hradec Králové , Sokolská 5005, Hradec Králové, Czech Republic
                IIBSant Pau, Hospital de la Santa Creu i Sant Pau, CiberCV , Barcelona, Spain
                Royal Marsden NHS Trust & Institute of Cancer Research , London, UK
                Division of Hematology/Oncology/Transplantation, University of Minnesota , Minneapolis, MN, USA
                University of Cyprus Medical School , Nicosia, Cyprus
                Department of Oncology and Hemato-Oncology, University of Milan , Milan, Italy
                IRCCS, European Institute of Oncology , Milan, Italy
                Patient Advocate , London, UK
                National Heart and Lung Institute, Imperial College London, and Cardio-Oncology Service, Royal Brompton Hospital , London, UK
                Cardiology department, La Paz University Hospital, IdiPAZ Research Institute , Madrid, Spain
                Author notes
                Corresponding author. Tel: +44207 8483201, Email: Gerry.lee@ 123456kcl.ac.uk

                Developed in collaboration with the Heart Failure Association of the European Society of Cardiology.

                Author information
                https://orcid.org/0000-0001-6385-8600
                https://orcid.org/0000-0002-9854-481X
                https://orcid.org/0000-0002-1316-8676
                https://orcid.org/0000-0002-2273-7228
                https://orcid.org/0000-0002-3075-1943
                https://orcid.org/0000-0003-1055-2231
                https://orcid.org/0000-0002-9935-8904
                https://orcid.org/0000-0002-5433-4810
                https://orcid.org/0000-0001-8364-3447
                Article
                qcac070
                10.1093/ehjqcco/qcac070
                9745663
                36316010
                c8e4124d-772a-4bb2-a831-6512bb9171cd
                © The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License ( https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@ 123456oup.com

                History
                : 12 October 2022
                : 21 October 2022
                : 24 November 2022
                Page count
                Pages: 7
                Funding
                Funded by: Horizon 2020, DOI 10.13039/100010661;
                Categories
                Review
                AcademicSubjects/MED00200

                quality indicators,cardio-oncology,assessment,treatment,cancer therapy-related cardiovascular toxicity,outcomes

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