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      Primary Stability Recognition of the Newly Designed Cementless Femoral Stem Using Digital Signal Processing

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          Abstract

          Stress shielding and micromotion are two major issues which determine the success of newly designed cementless femoral stems. The correlation of experimental validation with finite element analysis (FEA) is commonly used to evaluate the stress distribution and fixation stability of the stem within the femoral canal. This paper focused on the applications of feature extraction and pattern recognition using support vector machine (SVM) to determine the primary stability of the implant. We measured strain with triaxial rosette at the metaphyseal region and micromotion with linear variable direct transducer proximally and distally using composite femora. The root mean squares technique is used to feed the classifier which provides maximum likelihood estimation of amplitude, and radial basis function is used as the kernel parameter which mapped the datasets into separable hyperplanes. The results showed 100% pattern recognition accuracy using SVM for both strain and micromotion. This indicates that DSP could be applied in determining the femoral stem primary stability with high pattern recognition accuracy in biomechanical testing.

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          Most cited references43

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          Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue.

          The ability to determine trabecular bone tissue elastic and failure properties has biological and clinical importance. To date, trabecular tissue yield strains remain unknown due to experimental difficulties, and elastic moduli studies have reported controversial results. We hypothesized that the elastic and tensile and compressive yield properties of trabecular tissue are similar to those of cortical tissue. Effective tissue modulus and yield strains were calibrated for cadaveric human femoral neck specimens taken from 11 donors, using a combination of apparent-level mechanical testing and specimen-specific, high-resolution, nonlinear finite element modeling. The trabecular tissue properties were then compared to measured elastic modulus and tensile yield strain of human femoral diaphyseal cortical bone specimens obtained from a similar cohort of 34 donors. Cortical tissue properties were obtained by statistically eliminating the effects of vascular porosity. Results indicated that mean elastic modulus was 10% lower (p<0.05) for the trabecular tissue (18.0+/-2.8 GPa) than for the cortical tissue (19.9+/-1.8 GPa), and the 0.2% offset tensile yield strain was 15% lower for the trabecular tissue (0.62+/-0.04% vs. 0.73+/-0.05%, p<0.001). The tensile-compressive yield strength asymmetry for the trabecular tissue, 0.62 on average, was similar to values reported in the literature for cortical bone. We conclude that while the elastic modulus and yield strains for trabecular tissue are just slightly lower than those of cortical tissue, because of the cumulative effect of these differences, tissue strength is about 25% greater for cortical bone.
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            Mechanical validation of whole bone composite femur models.

            Composite synthetic models of the human femur have recently become commercially available as substitutes for cadaveric specimens. Their quick diffusion was justified by the advantages they offer as a substitute for real femurs. The present investigation concentrated on an extensive experimental validation of the mechanical behaviour of the whole bone composite model, compared to human fresh-frozen and dried-rehydrated specimens for different loading conditions. First, the viscoelastic behaviour of the models was investigated under simulated single leg stance loading, showing that the little time dependent phenomena observed tend to extinguish within a few minutes of the load application. The behaviour under axial loading was then studied by comparing the vertical displacement of the head as well as the axial strains, by application of a parametric descriptive model of the strain distribution. Finally, a four point bending test and a torsional test were performed to characterize the whole bone stiffness of the femur. In all these tests, the composite femurs were shown to fall well within the range for cadaveric specimens, with no significant differences being detected between the synthetic femurs and the two groups of cadaveric femurs. Moreover, the interfemur variability for the composite femurs was 20-200 times lower than that for the cadaveric specimens, thus allowing smaller differences to be characterized as significant using the same simple size, if the composite femurs are employed.
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              The compressive behavior of bone as a two-phase porous structure.

              Compression tests of human and bovine trabecular bone specimens with and without marrow in situ were conducted at strain rates of from 0.001 to 10.0 per second. A porous platen above the specimens allowed the escape of marrow during testing. The presence of marrow increased the strength, modulus, and energy absorption of specimens only at the highest strain rate of 10.0 per second. This enhancement of material properties at the highest strain rate was due primarily to the restricted viscous flow of marrow through the platen rather than the flow through the pores of the trabecular bone. In specimens without marrow, the strength was proportional to the square of the apparent density and the modulus was proportional to the cube of the apparent density. Both strength and modulus were approximately proportional to the strain rate raised to the 0.06 power. These power relationships, which were shown to hold for all bone in the skeleton, allow meaningful predictions of bone tissue strength and stiffness based on in vivo density measurements.
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                Author and article information

                Journal
                Biomed Res Int
                Biomed Res Int
                BMRI
                BioMed Research International
                Hindawi Publishing Corporation
                2314-6133
                2314-6141
                2014
                1 April 2014
                : 2014
                : 478248
                Affiliations
                1Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Lembah Pantai, Kuala Lumpur, Malaysia
                2Centre for Biomedical Engineering Transportation Research Alliance, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia
                3Department of Orthopaedic, Traumatology & Rehabilitation, Kuliyyah of Medicine, International Islamic University Malaysia, 25200 Kuantan, Pahang, Malaysia
                4Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia, 81310 Skudai, Johor, Malaysia
                Author notes
                *Sh-Hussain Salleh: hussain@ 123456fke.utm.my

                Academic Editor: Yoshinobu Sato

                Author information
                http://orcid.org/0000-0002-2956-6361
                Article
                10.1155/2014/478248
                3988726
                24800230
                ccfd1319-c272-42a0-b1e0-711b67a313d2
                Copyright © 2014 Mohd Yusof Baharuddin et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 15 November 2013
                : 20 February 2014
                : 6 March 2014
                Funding
                Funded by: Universiti Teknologi Malaysia
                Award ID: R.J.130000.7713.4J058
                Funded by: Universiti Teknologi Malaysia
                Award ID: Q.J130000.2436.00G31
                Funded by: Universiti Teknologi Malaysia
                Award ID: Q.J130000.2436.00G33
                Funded by: Ministry of Science and Technology Malaysia
                Award ID: 06-01-15-SF0119
                Funded by: http://dx.doi.org/10.13039/501100003093 Ministry of Higher Education, Malaysia
                Award ID: 9003-00200
                Categories
                Research Article

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