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      Fast and accurate view classification of echocardiograms using deep learning

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          Abstract

          Echocardiography is essential to cardiology. However, the need for human interpretation has limited echocardiography’s full potential for precision medicine. Deep learning is an emerging tool for analyzing images but has not yet been widely applied to echocardiograms, partly due to their complex multi-view format. The essential first step toward comprehensive computer-assisted echocardiographic interpretation is determining whether computers can learn to recognize these views. We trained a convolutional neural network to simultaneously classify 15 standard views (12 video, 3 still), based on labeled still images and videos from 267 transthoracic echocardiograms that captured a range of real-world clinical variation. Our model classified among 12 video views with 97.8% overall test accuracy without overfitting. Even on single low-resolution images, accuracy among 15 views was 91.7% vs. 70.2–84.0% for board-certified echocardiographers. Data visualization experiments showed that the model recognizes similarities among related views and classifies using clinically relevant image features. Our results provide a foundation for artificial intelligence-assisted echocardiographic interpretation.

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          Most cited references11

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          Visualizing datausing t-SNE

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            Machine-Learning Algorithms to Automate Morphological and Functional Assessments in 2D Echocardiography.

            Machine-learning models may aid cardiac phenotypic recognition by using features of cardiac tissue deformation.
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              ACCF/ASE/AHA/ASNC/HFSA/HRS/SCAI/SCCM/SCCT/SCMR 2011 Appropriate Use Criteria for Echocardiography. A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, American Society of Echocardiography, American Heart Association, American Society of Nuclear Cardiology, Heart Failure Society of America, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Critical Care Medicine, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic Resonance Endorsed by the American College of Chest Physicians.

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                Author and article information

                Journal
                101731738
                47837
                NPJ Digit Med
                NPJ Digit Med
                NPJ digital medicine
                2398-6352
                13 August 2018
                21 March 2018
                2018
                28 February 2019
                : 1
                : 6
                Affiliations
                [1 ]Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Lab, California Institute for Quantitative Biosciences (QB3), University of California at Berkeley, 208A Stanley Hall Room 1762, Berkeley, CA 94720, USA
                [2 ]Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue Dana 615, Boston, MA 02215, USA
                [3 ]Cardiovascular Research Institute, University of California, 555 Mission Bay Blvd South Rm 484, San Francisco 94143, USA
                Author notes
                Correspondence: Mohammad Mofrad ( mofrad@ 123456berkeley.edu ) or Rima Arnaout ( rima.arnaout@ 123456ucsf.edu )
                Article
                NIHMS985029
                10.1038/s41746-017-0013-1
                6395045
                30828647
                cd0b2e88-808f-41bb-a704-a8f96f876590

                This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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