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      Tocilizumab treatment effectively improves coronary artery involvement in patients with Takayasu arteritis

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          The American College of Rheumatology 1990 criteria for the classification of takayasu arteritis

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            Takayasu Arteritis

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              Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial.

              Interleukin-6 (IL-6) contributes to atherosclerotic plaque destabilization and is involved in myocardial injury during ischaemia-reperfusion. Interleukin-6 is therefore a potential therapeutic target in myocardial infarction (MI). We hypothesized that the IL-6 receptor antagonist tocilizumab would attenuate inflammation, and secondarily reduce troponin T (TnT) release in non-ST-elevation MI (NSTEMI).
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                Author and article information

                Journal
                Clinical Rheumatology
                Clin Rheumatol
                Springer Science and Business Media LLC
                0770-3198
                1434-9949
                March 6 2020
                Article
                10.1007/s10067-020-05005-7
                32144625
                cdbbbd64-8d33-451f-adc7-68dac59efd8e
                © 2020

                http://www.springer.com/tdm

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