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      Lymph Vessels of the Transplanted Kidney

      , ,

      Nephron

      S. Karger AG

      Transplantation, Kidney, Lymphatics

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          Abstract

          Lymph vessels were evaluated in 20 transplanted canine kidneys. Prior to the occurrence of morphological rejection changes, transplants with good blood flow rates show areas with dilated but, less frequently, also undilated lymph vessels. In transplants with the presence of a rejection infiltrate and a decrease of the blood flow rate of 21–50% the lymph vessels may be focally dilated or, in contrast, narrowed by the cells of the rejection infiltrate. Numerous vesicles and vacuoles can be seen within the cytoplasm of endothelial cells. Interendothelial junctions may be occasionally open, the walls of endothelial cells become attenuated, and disintegration of the cell membrane is followed by a focal destruction of the wall and the development of defects. Cells of the rejection infiltrate penetrate through the gaps in the wall of the lymph vessels. The possible mechanism of the disintegration is discussed in this paper.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1986
          1986
          05 December 2008
          : 44
          : 2
          : 136-141
          Affiliations
          Department of Anatomy and Pathology, Faculty of General Medicine, Charles University, Prague, Czechoslovakia
          Article
          184218 Nephron 1986;44:136–141
          10.1159/000184218
          3534608
          © 1986 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 6
          Categories
          Original Paper

          Cardiovascular Medicine, Nephrology

          Lymphatics, Transplantation, Kidney

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